biostudies-literatureDwyer AANICHD NIH HHS598-605https://www.ebi.ac.uk/biostudies/studies/S-EPMC8284837biostudies-literatureUnknown30(2)Patients often have difficulty understanding genetic test reports. Technical language and jargon can impede comprehension and limit patients using results to act on findings. One potential way to improve patient understanding of genetic test reports is to provide patient-facing materials. This study aimed to examine understandability and actionability of co-created patient-facing materials for genetic test results in a research context. We combined interprofessional perspectives and patient engagement to co-create patient-facing materials for patients undergoing research genetic testing for congenital hypogonadotropic hypogonadism (Kallmann syndrome). The iterative development process was guided by principles of health literacy and human-centered design (i.e., design thinking). ReadabilityJournal of genetic counselingEvaluating co-created patient-facing materials to increase understanding of genetic test results.PMC8284837R37 HD043341K23 HD097296R01 HD096324P50HD028138P50 HD028138Smith NLippincott MFBalasubramanian RPlummer LSeminara SBDwyer AAAu MGfalseEvaluating co-created patient-facing materials to increase understanding of genetic test results.Patients often have difficulty understanding genetic test reports. Technical language and jargon can impede comprehension and limit patients using results to act on findings. One potential way to improve patient understanding of genetic test reports is to provide patient-facing materials. This study aimed to examine understandability and actionability of co-created patient-facing materials for genetic test results in a research context. We combined interprofessional perspectives and patient engagement to co-create patient-facing materials for patients undergoing research genetic testing for congenital hypogonadotropic hypogonadism (Kallmann syndrome). The iterative development process was guided by principles of health literacy and human-centered design (i.e., design thinking). Readability2021-01-01T00:00:00Z2021 Apr2025-04-22T21:56:40.871Z2025-04-06T03:52:13.457ZS-EPMC82848373309836710.1002/jgc4.1348