biostudies-literatureUnknown21(1)Barcot O<h4>Background</h4>Initially, the Cochrane risk of bias (RoB) tool had a domain for "blinding of participants, personnel and outcome assessors". In the 2011 tool, the assessment of blinding was split into two domains: blinding of participants and personnel (performance bias) and blinding of outcome assessors (detection bias). The aims of this study were twofold; first, to analyze the frequency of usage of the joint blinding domain (a single domain for performance and detection bias), and second, to assess the proportion of adequate assessments made in the joint versus single RoB domains for blinding by comparing whether authors' RoB judgments were supported by explanatory comments in line with the Cochrane Handbook recommendations.<h4>Methods</h4>We extracted information about the assessmeBMC medical research methodology149https://www.ebi.ac.uk/biostudies/studies/S-EPMC8286598biostudies-literatureAssessing the risk of performance and detection bias in Cochrane reviews as a joint domain is less accurate compared to two separate domains.PMC8286598Boric MDosenovic SPuljak LBarcot OfalseAssessing the risk of performance and detection bias in Cochrane reviews as a joint domain is less accurate compared to two separate domains.<h4>Background</h4>Initially, the Cochrane risk of bias (RoB) tool had a domain for "blinding of participants, personnel and outcome assessors". In the 2011 tool, the assessment of blinding was split into two domains: blinding of participants and personnel (performance bias) and blinding of outcome assessors (detection bias). The aims of this study were twofold; first, to analyze the frequency of usage of the joint blinding domain (a single domain for performance and detection bias), and second, to assess the proportion of adequate assessments made in the joint versus single RoB domains for blinding by comparing whether authors' RoB judgments were supported by explanatory comments in line with the Cochrane Handbook recommendations.<h4>Methods</h4>We extracted information about the assessme2021-01-01T00:00:00Z2021 Jul2026-05-08T00:23:39.315Z2025-05-18T12:41:16.97ZS-EPMC82865983427543710.1186/s12874-021-01339-1