{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Li Y"],"funding":["NIBIB NIH HHS","NIA NIH HHS","NIMH NIH HHS","NINDS NIH HHS","National Institutes of Health","NIH HHS"],"pagination":["1917-1928"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8295231"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["86(4)"],"pubmed_abstract":["<h4>Purpose</h4>The ability to measure cerebral vascular compliance (VC) is important in the evaluation of vascular diseases. Additionally, quantification of arterial wall pulsation in the brain may be useful for understanding the driving force of the recently discovered glymphatic system. Our goal is to develop an MRI technique to measure VC and arterial wall pulsation in major intracranial vessels.<h4>Methods</h4>A total of 17 healthy subjects were studied on a 3T MRI system. The technique, called VaCom-PCASL, uses pseudo-continuous arterial spin labeling (PCASL) to obtain pure blood vessel signal, uses a 3D radial acquisition, and applies a golden-angle radial sparse parallel (GRASP) algorithm for image reconstruction. The k-space data were retrospectively sorted into different cardiac "],"journal":["Magnetic resonance in medicine"],"pubmed_title":["Three-dimensional assessment of brain arterial compliance: Technical development, comparison with aortic pulse wave velocity, and age effect."],"pmcid":["PMC8295231"],"funding_grant_id":["R01 AG064792","R01 AG071515","RF1 AG071515","R01 NS106711","R01 NS106702","S10 OD021648","P41 EB015909","P41 EB031771","R01 MH084021"],"pubmed_authors":["Li Y","Qiao Y","Lim C","Lu H","Schar M","Jiang D","Pillai JJ"],"additional_accession":[]},"is_claimable":false,"name":"Three-dimensional assessment of brain arterial compliance: Technical development, comparison with aortic pulse wave velocity, and age effect.","description":"<h4>Purpose</h4>The ability to measure cerebral vascular compliance (VC) is important in the evaluation of vascular diseases. Additionally, quantification of arterial wall pulsation in the brain may be useful for understanding the driving force of the recently discovered glymphatic system. Our goal is to develop an MRI technique to measure VC and arterial wall pulsation in major intracranial vessels.<h4>Methods</h4>A total of 17 healthy subjects were studied on a 3T MRI system. The technique, called VaCom-PCASL, uses pseudo-continuous arterial spin labeling (PCASL) to obtain pure blood vessel signal, uses a 3D radial acquisition, and applies a golden-angle radial sparse parallel (GRASP) algorithm for image reconstruction. The k-space data were retrospectively sorted into different cardiac ","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Oct","modification":"2025-04-18T12:56:40.529Z","creation":"2025-02-19T02:24:15.174Z"},"accession":"S-EPMC8295231","cross_references":{"pubmed":["33977546"],"doi":["10.1002/mrm.28835"]}}