biostudies-literatureMagnani CJNCI NIH HHS1159-1168https://www.ebi.ac.uk/biostudies/studies/S-EPMC8296852biostudies-literatureUnknown205(4)<h4>Purpose</h4>Clinical trials require significant resources, but benefits are only realized after trial completion and dissemination of results. We comprehensively assessed early discontinuation, registry results reporting, and publication by trial sponsor and subspecialty in urology trials.<h4>Materials and methods</h4>We assessed trial registrations from 2007 to 2019 on ClinicalTrials.gov and publication data from PubMed®/MEDLINE®. Associations between sponsor or subspecialty with early discontinuation were assessed using Cox proportional hazards and results reporting or publication with logistic regression at 3 years after completion.<h4>Results</h4>Of 8,636 trials 3,541 (41.0%) were completed and 999 (11.6%) were discontinued. Of completed trials 26.9% reported results and 21.6% wereThe Journal of urologyClinical Trial Outcomes in Urology: Assessing Early Discontinuation, Results Reporting and Publication in ClinicalTrials.Gov Registrations 2007-2019.PMC8296852R01 CA183962Steinberg JRHernandez-Boussard TBrooks JDDriscoll CBell ATurner BEMagnani CJZhang XLarson JHarmange CIWeeks BTYou JGfalseClinical Trial Outcomes in Urology: Assessing Early Discontinuation, Results Reporting and Publication in ClinicalTrials.Gov Registrations 2007-2019.<h4>Purpose</h4>Clinical trials require significant resources, but benefits are only realized after trial completion and dissemination of results. We comprehensively assessed early discontinuation, registry results reporting, and publication by trial sponsor and subspecialty in urology trials.<h4>Materials and methods</h4>We assessed trial registrations from 2007 to 2019 on ClinicalTrials.gov and publication data from PubMed®/MEDLINE®. Associations between sponsor or subspecialty with early discontinuation were assessed using Cox proportional hazards and results reporting or publication with logistic regression at 3 years after completion.<h4>Results</h4>Of 8,636 trials 3,541 (41.0%) were completed and 999 (11.6%) were discontinued. Of completed trials 26.9% reported results and 21.6% were2021-01-01T00:00:00Z2021 Apr2025-04-29T11:28:21.384Z2025-04-06T19:55:02.035ZS-EPMC82968523307961810.1097/JU.000000000000143210.1097/ju.0000000000001432