{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Jiao Y"],"funding":["Fondation ARC pour la Recherche sur le Cancer","Institut National Du Cancer"],"pagination":["155"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8320036"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["21(1)"],"pubmed_abstract":["<h4>Background</h4>Linking independent sources of data describing the same individuals enable innovative epidemiological and health studies but require a robust record linkage approach. We describe a hybrid record linkage process to link databases from two independent ongoing French national studies, GEMO (Genetic Modifiers of BRCA1 and BRCA2), which focuses on the identification of genetic factors modifying cancer risk of BRCA1 and BRCA2 mutation carriers, and GENEPSO (prospective cohort of BRCAx mutation carriers), which focuses on environmental and lifestyle risk factors.<h4>Methods</h4>To identify as many as possible of the individuals participating in the two studies but not registered by a shared identifier, we combined probabilistic record linkage (PRL) and supervised machine learni"],"journal":["BMC medical research methodology"],"pubmed_title":["A new hybrid record linkage process to make epidemiological databases interoperable: application to the GEMO and GENEPSO studies involving BRCA1 and BRCA2 mutation carriers."],"pmcid":["PMC8320036"],"funding_grant_id":["TRANSCAN-JTC2012, n°2014-008","SHS-E-SP 18-015","2013-1-BCB-01-ICH-1","PJA 20151203365"],"pubmed_authors":["Ingster O","Peysselon M","Vennin P","Warcoin M","Cohen-Haguenauer O","Mouret-Fourme E","Leroux D","Leone M","Calender A","GEMO Study Collaborators","Fert-Ferrer S","Rossi A","GENEPSO Study Collaborators","Berthet P","Revillion F","Guimbaud R","Bressac-de-Paillerets B","Delnatte C","Bertolone G","Coulet F","Sevenet N","Toulas C","Baurand A","Caron O","Jacquot C","Guillaud-Bataille M","Longy M","Faivre L","Lortholary A","Lallaoui H","Adenis C","Beauvallet J","Mortemousque I","Popovici C","Mebirouk N","Kientz C","Tennevet I","Bonnet F","Dugast C","Zattara-Cannoni H","Harmand PO","Maugard C","Collonge-Rame MA","Coupier I","Tinat J","Eisinger F","Lizard S","Lejeune S","Barouk-Simonet E","Goussot V","Sokolowska J","Eon-Marchais S","Buecher B","Lauge A","Laurent M","Bignon YJ","Vaur D","Sobol H","Damette A","Lesueur F","Coron F","Lasset C","Mari V","Pujol P","Bourdon V","Soubrier F","Prieur F","Bonadona V","Gladieff L","Andrieu N","Vilquin P","Dreyfus H","Dumont A","Bezieau S","Gilbert B","Sawka C","Bronner M","Manouvrier-Hanu S","Gesta P","Chiesa J","Nogues C","Uhrhammer N","Muller D","Noguchi T","Nguyen TD","Giraud S","Remenieras A","Moretta J","Lebrun M","Dondon MG","Azencott CA","Caputo SM","Rebischung C","Venat-Bouvet L","Frenay M","Molina-Gomes D","Fricker JP","Laborde L","Castera L","Luporsi E","Bubien V","Boutry-Kryza N","Demange L","Feillel V","Pontois P","Stoppa-Lyonnet D","Jiao Y","Colas C","Limacher JM","Gauthier-Villars M"],"additional_accession":[]},"is_claimable":false,"name":"A new hybrid record linkage process to make epidemiological databases interoperable: application to the GEMO and GENEPSO studies involving BRCA1 and BRCA2 mutation carriers.","description":"<h4>Background</h4>Linking independent sources of data describing the same individuals enable innovative epidemiological and health studies but require a robust record linkage approach. We describe a hybrid record linkage process to link databases from two independent ongoing French national studies, GEMO (Genetic Modifiers of BRCA1 and BRCA2), which focuses on the identification of genetic factors modifying cancer risk of BRCA1 and BRCA2 mutation carriers, and GENEPSO (prospective cohort of BRCAx mutation carriers), which focuses on environmental and lifestyle risk factors.<h4>Methods</h4>To identify as many as possible of the individuals participating in the two studies but not registered by a shared identifier, we combined probabilistic record linkage (PRL) and supervised machine learni","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Jul","modification":"2026-07-16T13:59:00.214Z","creation":"2026-07-09T11:02:45.917Z"},"accession":"S-EPMC8320036","cross_references":{"pubmed":["34325649"],"doi":["10.1186/s12874-021-01299-6"]}}