biostudies-literatureWu YChina Scholarship CouncilBreast Cancer Research FoundationWorld Health OrganizationNCI NIH HHSNIH450-461https://www.ebi.ac.uk/biostudies/studies/S-EPMC8326053biostudies-literatureUnknown114(2)<h4>Background</h4>Epidemiologic studies examining the relations between dairy product and calcium intakes and breast cancer have been inconclusive, especially for tumor subtypes.<h4>Objective</h4>To evaluate the associations between intakes of specific dairy products and calcium and risk of breast cancer overall and for subtypes defined by estrogen receptor (ER) status.<h4>Method</h4>We pooled the individual-level data of over 1 million women who were followed for a maximum of 8-20 years across studies. Associations were evaluated for dairy product and calcium intakes and risk of incident invasive breast cancer overall (n = 37,861 cases) and by subtypes defined by ER status. Study-specific multivariable hazard ratios (HRs) were estimated and then combined using random-effects models.<h4>RThe American journal of clinical nutritionDairy foods, calcium, and risk of breast cancer overall and for subtypes defined by estrogen receptor status: a pooled analysis of 21 cohort studies.PMC8326053U01 CA182934CA55075001K01 CA212056P01 CA055075U01 CA167462Willett WCBethea TNRohan TEHuang RLarsson SCSieri SWang MPalmer JRPrizment AWeiderpass EMonroe KRVisvanathan KKrogh VFreedman NDMiller ABTsugane SGiles GGSandin SChen YGierach GLWolk AZeleniuch-Jacquotte AWu YRobien KSmith-Warner SAMilne RLGaudet MMLiao LMZiegler RGReynolds Pvan den Brandt PAMcCullough MLChen CEliassen AHWilkens LRSinha RSawada NStolzenberg-Solomon RZNeuhouser MLBernstein LfalseDairy foods, calcium, and risk of breast cancer overall and for subtypes defined by estrogen receptor status: a pooled analysis of 21 cohort studies.<h4>Background</h4>Epidemiologic studies examining the relations between dairy product and calcium intakes and breast cancer have been inconclusive, especially for tumor subtypes.<h4>Objective</h4>To evaluate the associations between intakes of specific dairy products and calcium and risk of breast cancer overall and for subtypes defined by estrogen receptor (ER) status.<h4>Method</h4>We pooled the individual-level data of over 1 million women who were followed for a maximum of 8-20 years across studies. Associations were evaluated for dairy product and calcium intakes and risk of incident invasive breast cancer overall (n = 37,861 cases) and by subtypes defined by ER status. Study-specific multivariable hazard ratios (HRs) were estimated and then combined using random-effects models.<h4>R2021-01-01T00:00:00Z2021 Aug2025-04-19T20:43:28.481Z2025-02-19T03:58:36.724ZS-EPMC83260533396485910.1093/ajcn/nqab097