{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Donadel DG"],"funding":["Committee for the Development of Higher Education Personnel—CAPES","Postgraduate Research Group at the Hospital de Clínicas de Porto Alegre","National Council for Scientific and Technological Development - CNPq"],"pagination":["15754"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8333354"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(1)"],"pubmed_abstract":["The delta value of oxyhemoglobin (Δ-HbO) determined by functional near-infrared spectroscopy at prefrontal cortex (PFC) and motor cortex (MC) based on primary (25 °C) and secondary (5 °C) thermal stimuli presented a larger peak latency at left MC in fibromyalgia than in controls. The difference between HbO concentration 15 s after the thermal stimuli ending and HbO concentration before the thermal stimuli onset (Δ-HbO*) at left PFC increased 47.82% in fibromyalgia and 76.66% in controls. This value had satisfactory discriminatory properties to differentiate cortical activation in fibromyalgia versus controls. A receiver operator characteristics (ROC) analysis showed the Δ-HbO* cutoffs of - 0.175 at left PFC and - 0.205 at right PFC offer sensitivity and specificity of at least 80% in scree"],"journal":["Scientific reports"],"pubmed_title":["The mapping of cortical activation by near-infrared spectroscopy might be a biomarker related to the severity of fibromyalgia symptoms."],"pmcid":["PMC8333354"],"funding_grant_id":["grant nos. 302688/2017-0 and 420826/2018-1 to W. C.","(grant no. 20170330)."],"pubmed_authors":["Torres ILS","Donadel DG","Zortea M","Caumo W","Fregni F"],"additional_accession":[]},"is_claimable":false,"name":"The mapping of cortical activation by near-infrared spectroscopy might be a biomarker related to the severity of fibromyalgia symptoms.","description":"The delta value of oxyhemoglobin (Δ-HbO) determined by functional near-infrared spectroscopy at prefrontal cortex (PFC) and motor cortex (MC) based on primary (25 °C) and secondary (5 °C) thermal stimuli presented a larger peak latency at left MC in fibromyalgia than in controls. The difference between HbO concentration 15 s after the thermal stimuli ending and HbO concentration before the thermal stimuli onset (Δ-HbO*) at left PFC increased 47.82% in fibromyalgia and 76.66% in controls. This value had satisfactory discriminatory properties to differentiate cortical activation in fibromyalgia versus controls. A receiver operator characteristics (ROC) analysis showed the Δ-HbO* cutoffs of - 0.175 at left PFC and - 0.205 at right PFC offer sensitivity and specificity of at least 80% in scree","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Aug","modification":"2025-04-19T00:29:34.503Z","creation":"2022-02-11T04:15:31.649Z"},"accession":"S-EPMC8333354","cross_references":{"pubmed":["34344913"],"doi":["10.1038/s41598-021-94456-2"]}}