{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Mason D"],"funding":["Economic and Social Research Council","King's College London","Medical Research Council"],"pagination":["3165-3179"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8349337"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["51(9)"],"pubmed_abstract":["Longitudinal studies have generally reported poor outcomes in adulthood for the majority of individuals (c.50-60%) with autism. Several factors putatively predict outcome (e.g. IQ), but findings remain mixed. This paper presents an updated meta-analysis of autism outcome studies and extends previous findings with additional analyses (including meta-regression). A total of 4088 records was screened and 18 studies, involving 1199 individuals, were included in the quantitative analysis. Estimated percentages indicated that 20.0% of participants were rated as having a good outcome, 26.6% a fair outcome, and 49.3% a poor outcome. Meta-regression indicated that lower IQ in adulthood was predictive of poor outcome; other meta-regression models did not survive correction for multiple comparisons. "],"journal":["Journal of autism and developmental disorders"],"pubmed_title":["A Meta-analysis of Outcome Studies of Autistic Adults: Quantifying Effect Size, Quality, and Meta-regression."],"pmcid":["PMC8349337"],"funding_grant_id":["2106586"],"pubmed_authors":["Glaser K","Happe F","Kempton MJ","Stewart GR","Mason D","Capp SJ","Howlin P"],"additional_accession":[]},"is_claimable":false,"name":"A Meta-analysis of Outcome Studies of Autistic Adults: Quantifying Effect Size, Quality, and Meta-regression.","description":"Longitudinal studies have generally reported poor outcomes in adulthood for the majority of individuals (c.50-60%) with autism. Several factors putatively predict outcome (e.g. IQ), but findings remain mixed. This paper presents an updated meta-analysis of autism outcome studies and extends previous findings with additional analyses (including meta-regression). A total of 4088 records was screened and 18 studies, involving 1199 individuals, were included in the quantitative analysis. Estimated percentages indicated that 20.0% of participants were rated as having a good outcome, 26.6% a fair outcome, and 49.3% a poor outcome. Meta-regression indicated that lower IQ in adulthood was predictive of poor outcome; other meta-regression models did not survive correction for multiple comparisons. ","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Sep","modification":"2026-07-16T09:13:20.864Z","creation":"2026-07-09T10:52:12.694Z"},"accession":"S-EPMC8349337","cross_references":{"pubmed":["33200352"],"doi":["10.1007/s10803-020-04763-2"]}}