biostudies-literatureUnknown36Wang S<h4>Background</h4>The optimal antithrombotic strategy, especially regarding oral anticoagulants (OACs) for atrial fibrillation (AF) patients with bleeding and thrombosis risk after percutaneous coronary intervention (PCI), remains unknown. This study explored the optimal oral anticoagulants for AF patients after PCI using a <i>meta</i>-analysis.<h4>Methods</h4>Randomised controlled trials were identified from PubMed, Embase, and the Cochrane Library through December 2020. Risk ratios, 95% confidence intervals, and random-effects models were used to compare different antithrombotic strategies through network <i>meta</i>-analysis, and the combination of antithrombotic agents was ranked according to the surface under the cumulative ranking curve and rankograms. Interval plots were drawn to oInternational journal of cardiology. Heart & vasculature100850https://www.ebi.ac.uk/biostudies/studies/S-EPMC8349768biostudies-literatureOptimisation of oral anticoagulants for patients with atrial fibrillation within 12 months after percutaneous coronary intervention: A <i>meta</i>-analysis and systematic review.PMC8349768Liu YYin DWang SZuo HTian YZhang HWang YWang LfalseOptimisation of oral anticoagulants for patients with atrial fibrillation within 12 months after percutaneous coronary intervention: A <i>meta</i>-analysis and systematic review.<h4>Background</h4>The optimal antithrombotic strategy, especially regarding oral anticoagulants (OACs) for atrial fibrillation (AF) patients with bleeding and thrombosis risk after percutaneous coronary intervention (PCI), remains unknown. This study explored the optimal oral anticoagulants for AF patients after PCI using a <i>meta</i>-analysis.<h4>Methods</h4>Randomised controlled trials were identified from PubMed, Embase, and the Cochrane Library through December 2020. Risk ratios, 95% confidence intervals, and random-effects models were used to compare different antithrombotic strategies through network <i>meta</i>-analysis, and the combination of antithrombotic agents was ranked according to the surface under the cumulative ranking curve and rankograms. Interval plots were drawn to o2021-01-01T00:00:00Z2021 Oct2025-05-29T22:26:58.761Z2022-02-11T07:59:36.663ZS-EPMC83497683440146810.1016/j.ijcha.2021.100850