{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Breves JP"],"funding":["National Institute of Diabetes and Digestive and Kidney Diseases","NIDDK NIH HHS","National Institutes of Health","National Institute of Food and Agriculture","National Science Foundation","National Oceanic and Atmospheric Administration"],"pagination":["111021"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8355173"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["260"],"pubmed_abstract":["Euryhaline fishes maintain hydromineral balance in a broad range of environmental salinities via the activities of multiple osmoregulatory organs, namely the gill, gastrointestinal tract, skin, kidney, and urinary bladder. Teleosts residing in freshwater (FW) environments are faced with the diffusive loss of ions and the osmotic gain of water, and, therefore, the kidney and urinary bladder reabsorb Na<sup>+</sup> and Cl<sup>-</sup> to support the production of dilute urine. Nonetheless, the regulated pathways for Na<sup>+</sup> and Cl<sup>-</sup> transport by euryhaline fishes, especially in the urinary bladder, have not been fully resolved. Here, we first investigated the ultrastructure of epithelial cells within the urinary bladder of FW-acclimated Mozambique tilapia (Oreochromis mossamb"],"journal":["Comparative biochemistry and physiology. Part A, Molecular & integrative physiology"],"pubmed_title":["Enhanced expression of ncc1 and clc2c in the kidney and urinary bladder accompanies freshwater acclimation in Mozambique tilapia."],"pmcid":["PMC8355173"],"funding_grant_id":["R21DK111775","R21 DK111775","NA18OAR4170347","IOS-1755016","IOS-1755131"],"pubmed_authors":["Petro-Sakuma CK","Breves JP","Koltenyuk V","Seale AP","Celino-Brady FT","Nelson NN"],"additional_accession":[]},"is_claimable":false,"name":"Enhanced expression of ncc1 and clc2c in the kidney and urinary bladder accompanies freshwater acclimation in Mozambique tilapia.","description":"Euryhaline fishes maintain hydromineral balance in a broad range of environmental salinities via the activities of multiple osmoregulatory organs, namely the gill, gastrointestinal tract, skin, kidney, and urinary bladder. Teleosts residing in freshwater (FW) environments are faced with the diffusive loss of ions and the osmotic gain of water, and, therefore, the kidney and urinary bladder reabsorb Na<sup>+</sup> and Cl<sup>-</sup> to support the production of dilute urine. Nonetheless, the regulated pathways for Na<sup>+</sup> and Cl<sup>-</sup> transport by euryhaline fishes, especially in the urinary bladder, have not been fully resolved. Here, we first investigated the ultrastructure of epithelial cells within the urinary bladder of FW-acclimated Mozambique tilapia (Oreochromis mossamb","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Oct","modification":"2025-04-03T22:35:12.026Z","creation":"2024-10-16T04:23:25.01Z"},"accession":"S-EPMC8355173","cross_references":{"pubmed":["34174427"],"doi":["10.1016/j.cbpa.2021.111021"]}}