{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Rosenthal M"],"funding":["National Cancer Institute","NCI NIH HHS"],"pagination":["690-698"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8356859"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["6(4)"],"pubmed_abstract":["<h4>Importance</h4>This study reports the impact of laser surgery on quality of life in patients with oral cavity lesions.<h4>Objective</h4>To compare postoperative pain and quality of life in patients treated with flexible fiberoptic CO<sub>2</sub> laser vs electrocautery in patients with oral cavity precancerous lesions and early stage cancers.<h4>Design</h4>Randomized controlled trial.<h4>Setting</h4>Single center.<h4>Participants</h4>Patients with premalignant oral cavity lesions and early stage oral cancer.<h4>Intervention</h4>Patients were randomized to have surgical resection using either flexible fiber carbon dioxide laser (Laser) or electrocautery (EC). The patients were then followed over a period of 28 days to assess for outcomes including pain, quality of life, performance stat"],"journal":["Laryngoscope investigative otolaryngology"],"pubmed_title":["Flexible fiber-based CO<sub>2</sub> laser vs monopolar cautery for resection of oral cavity lesions: A single center randomized controlled trial assessing pain and quality of life following surgery."],"pmcid":["PMC8356859"],"funding_grant_id":["P30 CA008748"],"pubmed_authors":["Wong RJ","Cohen MA","Morris LGT","Patel S","Baser RE","Shah JP","Boyle JO","Singh B","Ganly I","Migliacci J","Rosenthal M"],"additional_accession":[]},"is_claimable":false,"name":"Flexible fiber-based CO<sub>2</sub> laser vs monopolar cautery for resection of oral cavity lesions: A single center randomized controlled trial assessing pain and quality of life following surgery.","description":"<h4>Importance</h4>This study reports the impact of laser surgery on quality of life in patients with oral cavity lesions.<h4>Objective</h4>To compare postoperative pain and quality of life in patients treated with flexible fiberoptic CO<sub>2</sub> laser vs electrocautery in patients with oral cavity precancerous lesions and early stage cancers.<h4>Design</h4>Randomized controlled trial.<h4>Setting</h4>Single center.<h4>Participants</h4>Patients with premalignant oral cavity lesions and early stage oral cancer.<h4>Intervention</h4>Patients were randomized to have surgical resection using either flexible fiber carbon dioxide laser (Laser) or electrocautery (EC). The patients were then followed over a period of 28 days to assess for outcomes including pain, quality of life, performance stat","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Aug","modification":"2026-05-03T03:12:51.783Z","creation":"2022-02-11T08:32:27.165Z"},"accession":"S-EPMC8356859","cross_references":{"pubmed":["34401493"],"doi":["10.1002/lio2.572"]}}