biostudies-literatureUnknown12Mariam IMicroalgae, due to their unique properties, gained attention for producing promising feedstocks having high contents of proteins, antioxidants, carotenoids, and terpenoids for applications in nutraceutical and pharmaceutical industries. Optimizing production of the high-value renewables (HVRs) in microalgae requires an in-depth understanding of their functional relationship of the genes involved in these metabolic pathways. In the present study, bioinformatic tools were employed for characterization of the protein-encoding genes of methyl erythritol phosphate (MEP) pathway involved in carotenoid and squalene biosynthesis based upon their conserved motif/domain organization. Our analysis demonstrates nearly 200 putative genes showing a conservation pattern within divergent microalgal lineagFrontiers in microbiology693106https://www.ebi.ac.uk/biostudies/studies/S-EPMC8358449biostudies-literatureChanneling of Carbon Flux Towards Carotenogenesis in <i>Botryococcus braunii</i>: A Media Engineering Perspective.PMC8358449Kareya MSMariam INesamma AARehmanji MJutur PPfalseChanneling of Carbon Flux Towards Carotenogenesis in <i>Botryococcus braunii</i>: A Media Engineering Perspective.Microalgae, due to their unique properties, gained attention for producing promising feedstocks having high contents of proteins, antioxidants, carotenoids, and terpenoids for applications in nutraceutical and pharmaceutical industries. Optimizing production of the high-value renewables (HVRs) in microalgae requires an in-depth understanding of their functional relationship of the genes involved in these metabolic pathways. In the present study, bioinformatic tools were employed for characterization of the protein-encoding genes of methyl erythritol phosphate (MEP) pathway involved in carotenoid and squalene biosynthesis based upon their conserved motif/domain organization. Our analysis demonstrates nearly 200 putative genes showing a conservation pattern within divergent microalgal lineag2021-01-01T00:00:00Z20212025-04-05T15:08:06.615Z2022-02-11T07:18:02.969ZS-EPMC83584493439403210.3389/fmicb.2021.693106