{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["MacCready JS"],"funding":["Division of Molecular and Cellular Biosciences"],"pagination":["277-297"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8359340"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["116(1)"],"pubmed_abstract":["Carboxysomes are protein-based organelles essential for carbon fixation in cyanobacteria and proteobacteria. Previously, we showed that the cyanobacterial nucleoid is used to equally space out β-carboxysomes across cell lengths by a two-component system (McdAB) in the model cyanobacterium Synechococcus elongatus PCC 7942. More recently, we found that McdAB systems are widespread among β-cyanobacteria, which possess β-carboxysomes, but are absent in α-cyanobacteria, which possess structurally and phyletically distinct α-carboxysomes. Cyanobacterial α-carboxysomes are thought to have arisen in proteobacteria and then horizontally transferred into cyanobacteria, which suggests that α-carboxysomes in proteobacteria may also lack the McdAB system. Here, using the model chemoautotrophic proteoba"],"journal":["Molecular microbiology"],"pubmed_title":["The McdAB system positions α-carboxysomes in proteobacteria."],"pmcid":["PMC8359340"],"funding_grant_id":["1817478","1941966"],"pubmed_authors":["Vecchiarelli AG","Basalla JL","MacCready JS","Tran L","Hakim P"],"additional_accession":[]},"is_claimable":false,"name":"The McdAB system positions α-carboxysomes in proteobacteria.","description":"Carboxysomes are protein-based organelles essential for carbon fixation in cyanobacteria and proteobacteria. Previously, we showed that the cyanobacterial nucleoid is used to equally space out β-carboxysomes across cell lengths by a two-component system (McdAB) in the model cyanobacterium Synechococcus elongatus PCC 7942. More recently, we found that McdAB systems are widespread among β-cyanobacteria, which possess β-carboxysomes, but are absent in α-cyanobacteria, which possess structurally and phyletically distinct α-carboxysomes. Cyanobacterial α-carboxysomes are thought to have arisen in proteobacteria and then horizontally transferred into cyanobacteria, which suggests that α-carboxysomes in proteobacteria may also lack the McdAB system. Here, using the model chemoautotrophic proteoba","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Jul","modification":"2026-05-08T20:22:32.912Z","creation":"2022-02-11T08:27:37.338Z"},"accession":"S-EPMC8359340","cross_references":{"pubmed":["33638215"],"doi":["10.1111/mmi.14708"]}}