biostudies-literatureWu YChina Scholarship CouncilEuropean Research Council2420-2423https://www.ebi.ac.uk/biostudies/studies/S-EPMC8362199biostudies-literatureUnknown22(14)The fatty acid photodecarboxylase from Chlorella variabilis NC64 A (CvFAP) catalyses the light-dependent decarboxylation of fatty acids. Photoinactivation of CvFAP still represents one of the major limitations of this interesting enzyme en route to practical application. In this study we demonstrate that the photostability of CvFAP can easily be improved by the administration of medium-chain length carboxylic acids such as caprylic acid indicating that the best way of maintaining CvFAP stability is 'to keep the enzyme busy'.Chembiochem : a European journal of chemical biologyStabilisation of the Fatty Acid Decarboxylase from Chlorella variabilis by Caprylic Acid.PMC8362199966788Paul CEWu YHollmann FfalseStabilisation of the Fatty Acid Decarboxylase from Chlorella variabilis by Caprylic Acid.The fatty acid photodecarboxylase from Chlorella variabilis NC64 A (CvFAP) catalyses the light-dependent decarboxylation of fatty acids. Photoinactivation of CvFAP still represents one of the major limitations of this interesting enzyme en route to practical application. In this study we demonstrate that the photostability of CvFAP can easily be improved by the administration of medium-chain length carboxylic acids such as caprylic acid indicating that the best way of maintaining CvFAP stability is 'to keep the enzyme busy'.2021-01-01T00:00:00Z2021 Jul2025-05-29T22:27:49.954Z2025-05-29T22:27:49.954ZS-EPMC83621993400291910.1002/cbic.202100182