biostudies-literatureHoch MJNIBIB NIH HHSNIA NIH HHSNINDS NIH HHSNational Institute of Biomedical Imaging and BioengineeringNational Institute on Aging1437-1443https://www.ebi.ac.uk/biostudies/studies/S-EPMC8367627biostudies-literatureUnknown42(8)<h4>Background and purpose</h4>Diffusion MR imaging sequences essential for clinical neuroradiology imaging protocols may be accelerated with simultaneous multislice acquisitions. We tested whether simultaneous multislice-accelerated diffusion data were clinically equivalent to standard acquisitions.<h4>Materials and methods</h4>In this retrospective study, clinical diffusion sequences obtained before and after implementation of 2-slice simultaneous multislice acceleration and an altered diffusion gradient sampling scheme using the same 3T MRI scanner and 20-channel coil (<i>n</i> = 25 per group) were independently and blindly evaluated by 2 neuroradiologists for perceived quality, artifacts, and overall diagnostic utility. Diffusion tractography was performed in 13 patients both with and AJNR. American journal of neuroradiologySimultaneous Multislice for Accelerating Diffusion MRI in Clinical Neuroradiology Protocols.PMC8367627K23 AG048622R01 NS088040P41 EB017183P30 AG066512R01 NS039135AG048622-01P41EB017183Pacione DBruno MHoch MJFieremans ELui YWShepherd TMfalseSimultaneous Multislice for Accelerating Diffusion MRI in Clinical Neuroradiology Protocols.<h4>Background and purpose</h4>Diffusion MR imaging sequences essential for clinical neuroradiology imaging protocols may be accelerated with simultaneous multislice acquisitions. We tested whether simultaneous multislice-accelerated diffusion data were clinically equivalent to standard acquisitions.<h4>Materials and methods</h4>In this retrospective study, clinical diffusion sequences obtained before and after implementation of 2-slice simultaneous multislice acceleration and an altered diffusion gradient sampling scheme using the same 3T MRI scanner and 20-channel coil (<i>n</i> = 25 per group) were independently and blindly evaluated by 2 neuroradiologists for perceived quality, artifacts, and overall diagnostic utility. Diffusion tractography was performed in 13 patients both with and 2021-01-01T00:00:00Z2021 Aug2025-04-26T16:36:30.55Z2025-04-06T15:13:16.905ZS-EPMC83676273398594610.3174/ajnr.a714010.3174/ajnr.A7140