{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ludwig B"],"funding":["Austrian Science Fund FWF"],"pagination":["667191"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8378401"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12"],"pubmed_abstract":["<b>Background:</b> When investigating the neurobiology of suicidal behavior, Monoamino Oxidase A (<i>MAOA</i>) is one of the prime suspects to consider. Interestingly, <i>MAOA</i> dysregulation has also been associated with violent behavior in previous publications. In the present study, we aimed to establish an association between polymorphisms of the <i>MAOA</i> gene and methylation status of the <i>MAOA</i> gene Exon I, and suicide attempts with violent methods in a sample of affective disorder patients. <b>Methods:</b> Eight hundred fourteen Caucasian affective disorder patients were assessed at the Department of Psychiatry and Psychotherapy of the Medical University Vienna, the Karl Landsteiner University for Health and Science and Zentren für seelische Gesundheit, BBRZ-Med Leopoldau."],"journal":["Frontiers in psychiatry"],"pubmed_title":["Monoamino Oxidase A Gene Single-Nucleotide Polymorphisms and Methylation Status and the Risk of Violent Suicide Attempts in Affective Disorder Patients."],"pmcid":["PMC8378401"],"funding_grant_id":["KLI°220"],"pubmed_authors":["Fischer-Hansal D","Weinhaeusel A","Ludwig B","Bernegger A","Kapusta ND","Inaner M","Swoboda P","Senft B","Meisner L","Huber J","Schosser A","Carlberg L","Haslacher H","Aigner M","Kienesberger K","Kasper S","Mitschek MMM","Koller R","Affenzeller A","Schoenthaler S"],"additional_accession":[]},"is_claimable":false,"name":"Monoamino Oxidase A Gene Single-Nucleotide Polymorphisms and Methylation Status and the Risk of Violent Suicide Attempts in Affective Disorder Patients.","description":"<b>Background:</b> When investigating the neurobiology of suicidal behavior, Monoamino Oxidase A (<i>MAOA</i>) is one of the prime suspects to consider. Interestingly, <i>MAOA</i> dysregulation has also been associated with violent behavior in previous publications. In the present study, we aimed to establish an association between polymorphisms of the <i>MAOA</i> gene and methylation status of the <i>MAOA</i> gene Exon I, and suicide attempts with violent methods in a sample of affective disorder patients. <b>Methods:</b> Eight hundred fourteen Caucasian affective disorder patients were assessed at the Department of Psychiatry and Psychotherapy of the Medical University Vienna, the Karl Landsteiner University for Health and Science and Zentren für seelische Gesundheit, BBRZ-Med Leopoldau.","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021","modification":"2026-05-08T05:15:03.779Z","creation":"2022-02-11T09:45:16.588Z"},"accession":"S-EPMC8378401","cross_references":{"pubmed":["34421667"],"doi":["10.3389/fpsyt.2021.667191"]}}