{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lokker ME"],"funding":["ZonMw","The Netherlands Organisation for Health Research and Development"],"pagination":["335-343"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8380917"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(3)"],"pubmed_abstract":["<h4>Objectives</h4>At the end of life oral fluid intake is often reduced. Consensus about the most appropriate management for terminally ill patients with limited oral fluid intake is lacking. The objective of this study is to investigate to what extent the amount of fluid intake, preceding and during the dying phase, is related to the occurrence of death rattle and terminal restlessness.<h4>Methods</h4>A multicentre prospective observational study was performed. Data on the occurrence of death rattle and terminal restlessness, fluid intake and opioid use of patients expected to die within a few days or hours were collected.<h4>Results</h4>371 patients were included. Death rattle was reported at least once in 40% (n=149) of patients during the dying phase. Death rattle occurrence was not a"],"journal":["BMJ supportive & palliative care"],"pubmed_title":["Hydration and symptoms in the last days of life."],"pmcid":["PMC8380917"],"funding_grant_id":["11510004","Projectnummer 11510004"],"pubmed_authors":["Lokker ME","Oldenmenger WH","van der Rijt CCD","van Zuylen L","van der Heide A"],"additional_accession":[]},"is_claimable":false,"name":"Hydration and symptoms in the last days of life.","description":"<h4>Objectives</h4>At the end of life oral fluid intake is often reduced. Consensus about the most appropriate management for terminally ill patients with limited oral fluid intake is lacking. The objective of this study is to investigate to what extent the amount of fluid intake, preceding and during the dying phase, is related to the occurrence of death rattle and terminal restlessness.<h4>Methods</h4>A multicentre prospective observational study was performed. Data on the occurrence of death rattle and terminal restlessness, fluid intake and opioid use of patients expected to die within a few days or hours were collected.<h4>Results</h4>371 patients were included. Death rattle was reported at least once in 40% (n=149) of patients during the dying phase. Death rattle occurrence was not a","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Sep","modification":"2026-07-16T09:19:51.603Z","creation":"2026-07-09T10:46:47.91Z"},"accession":"S-EPMC8380917","cross_references":{"pubmed":["31473651"],"doi":["10.1136/bmjspcare-2018-001729"]}}