{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["111"],"submitter":["Chen Y"],"pubmed_abstract":["<h4>Aims</h4>To explore the contagiousness and new SARS-CoV-2 mutations in pediatric COVID-19.<h4>Methods</h4>This cohort study enrolled all pediatric patients admitted to 8 hospitals in Zhejiang Province of China between 21 January and 29 February 2020, their family members and close-contact classmates. Epidemiological, demographic, clinical and laboratory data were collected. Bioinformatics was used to analyze the features of SARS-CoV-2. Individuals were divided into 3 groups by the first-generation case: Groups 1 (unclear), 2 (adult), and 3 (child). The secondary attack rate (SAR) and R<sub>0</sub> were compared among the groups.<h4>Results</h4>The infection rate among 211 individuals was 64% (135/211). The SAR in Groups 2 and 3 was 71% (73/103) and 3% (1/30), respectively; the median R"],"journal":["International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases"],"pagination":["347-353"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8384730"],"repository":["biostudies-literature"],"pubmed_title":["The low contagiousness and new A958D mutation of SARS-CoV-2 in children: An observational cohort study."],"pmcid":["PMC8384730"],"pubmed_authors":["Hong L","Wu N","Chen J","Lu X","Wang J","Zhang Q","Li W","Cang X","Ni Y","Zheng J","Shu Q","Li S","Chen Z","Ye S","Fan L","Fu J","Chen Y","Wang W","Yao H","Xu W","Shang S","Cao Q"],"additional_accession":[]},"is_claimable":false,"name":"The low contagiousness and new A958D mutation of SARS-CoV-2 in children: An observational cohort study.","description":"<h4>Aims</h4>To explore the contagiousness and new SARS-CoV-2 mutations in pediatric COVID-19.<h4>Methods</h4>This cohort study enrolled all pediatric patients admitted to 8 hospitals in Zhejiang Province of China between 21 January and 29 February 2020, their family members and close-contact classmates. Epidemiological, demographic, clinical and laboratory data were collected. Bioinformatics was used to analyze the features of SARS-CoV-2. Individuals were divided into 3 groups by the first-generation case: Groups 1 (unclear), 2 (adult), and 3 (child). The secondary attack rate (SAR) and R<sub>0</sub> were compared among the groups.<h4>Results</h4>The infection rate among 211 individuals was 64% (135/211). The SAR in Groups 2 and 3 was 71% (73/103) and 3% (1/30), respectively; the median R","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Oct","modification":"2026-05-08T08:20:30.102Z","creation":"2022-02-11T12:03:30.43Z"},"accession":"S-EPMC8384730","cross_references":{"pubmed":["34454120"],"doi":["10.1016/j.ijid.2021.08.036"]}}