{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12"],"submitter":["Xi S"],"pubmed_abstract":["<b>Background:</b> Ciji-Hua'ai-Baosheng II Formula (CHB-II-F) is a traditional Chinese medicine formula, which specifically targets different aspects of chemotherapy-induced adverse effects in patients with cancer. In our clinical application, CHB-II-F significantly alleviated chemotherapy-induced anorexia (loss of appetite) and improved the quality of life for patients with tumor during and after chemotherapy. However, the mechanism of CHB-II-F in alleviation of chemotherapy-induced anorexia remains to be further investigated. <b>Aim of Study:</b> To explore the therapeutic effect and mechanism of CHB-II-F on chemotherapy-induced anorexia in the mice model of H<sub>22</sub> hepatoma. <b>Materials and Methods:</b> A total of 72 Kunming mice of SPF grade were inoculated subcutaneously with "],"journal":["Frontiers in pharmacology"],"pagination":["715824"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8416666"],"repository":["biostudies-literature"],"pubmed_title":["The Ciji-Hua'ai-Baosheng II Formula Attenuates Chemotherapy-Induced Anorexia in Mice With H<sub>22</sub> Hepatocellular Carcinoma."],"pmcid":["PMC8416666"],"pubmed_authors":["Guo X","Lu D","Xi S","Gong Y","Gao C","Zhao Y","Fu B","Li Y","Huang S","Zhai X","Wang Y","Qian L","Wang Z"],"additional_accession":[]},"is_claimable":false,"name":"The Ciji-Hua'ai-Baosheng II Formula Attenuates Chemotherapy-Induced Anorexia in Mice With H<sub>22</sub> Hepatocellular Carcinoma.","description":"<b>Background:</b> Ciji-Hua'ai-Baosheng II Formula (CHB-II-F) is a traditional Chinese medicine formula, which specifically targets different aspects of chemotherapy-induced adverse effects in patients with cancer. In our clinical application, CHB-II-F significantly alleviated chemotherapy-induced anorexia (loss of appetite) and improved the quality of life for patients with tumor during and after chemotherapy. However, the mechanism of CHB-II-F in alleviation of chemotherapy-induced anorexia remains to be further investigated. <b>Aim of Study:</b> To explore the therapeutic effect and mechanism of CHB-II-F on chemotherapy-induced anorexia in the mice model of H<sub>22</sub> hepatoma. <b>Materials and Methods:</b> A total of 72 Kunming mice of SPF grade were inoculated subcutaneously with ","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021","modification":"2025-06-01T00:30:07.166Z","creation":"2022-02-11T10:17:27.374Z"},"accession":"S-EPMC8416666","cross_references":{"pubmed":["34489705"],"doi":["10.3389/fphar.2021.715824"]}}