{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhang H"],"funding":["the National Key Research and Development Program of China","National Natural Science Foundation of China","Science and Technology Project of Tianjin Municipal Health Commission","Clinical Trial Project of Tianjin Medical University","Bethune Charitable Foundation-Excelsior Surgical Fund"],"pagination":["6149-6164"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8419772"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10(17)"],"pubmed_abstract":["<h4>Background</h4>The purpose of this study was to assess the prognostic performance of the log odds of positive lymph nodes (LODDS) value compared with the pathological N stage and lymph node ratio (LNR) in patients with esophageal squamous cell carcinoma (ESCC).<h4>Method</h4>In total 1144 patients diagnosed with ESCC from the Surveillance, Epidemiology, and End Results (SEER) database and 930 patients from our validation cohort were eligible. Kaplan-Meier plotter and multivariate Cox proportional hazards models were conducted to investigate the prognostic value of the N stage, LNR stage, and LODDS stage. The homogeneity, discriminatory ability, and monotonicity of these variables were evaluated using the linear trend χ<sup>2</sup> test, likelihood ratio χ<sup>2</sup> test, Akaike infor"],"journal":["Cancer medicine"],"pubmed_title":["The prognostic performance of the log odds of positive lymph nodes in patients with esophageal squamous cell carcinoma: A population study of the US SEER database and a Chinese single-institution cohort."],"pmcid":["PMC8419772"],"funding_grant_id":["2016YFC0901401","2017kylc006","82002551","HZB-20190528-18","81772619","KJ20119"],"pubmed_authors":["Yang Y","Zhang H","Zhu K","Jia R","Tang P","Ren P","Xiao W","Gong L","Yu Z"],"additional_accession":[]},"is_claimable":false,"name":"The prognostic performance of the log odds of positive lymph nodes in patients with esophageal squamous cell carcinoma: A population study of the US SEER database and a Chinese single-institution cohort.","description":"<h4>Background</h4>The purpose of this study was to assess the prognostic performance of the log odds of positive lymph nodes (LODDS) value compared with the pathological N stage and lymph node ratio (LNR) in patients with esophageal squamous cell carcinoma (ESCC).<h4>Method</h4>In total 1144 patients diagnosed with ESCC from the Surveillance, Epidemiology, and End Results (SEER) database and 930 patients from our validation cohort were eligible. Kaplan-Meier plotter and multivariate Cox proportional hazards models were conducted to investigate the prognostic value of the N stage, LNR stage, and LODDS stage. The homogeneity, discriminatory ability, and monotonicity of these variables were evaluated using the linear trend χ<sup>2</sup> test, likelihood ratio χ<sup>2</sup> test, Akaike infor","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Sep","modification":"2025-04-22T20:49:13.097Z","creation":"2022-02-11T10:48:08.511Z"},"accession":"S-EPMC8419772","cross_references":{"pubmed":["34240812"],"doi":["10.1002/cam4.4120"]}}