biostudies-literatureUnknown9(16)Zhao R<h4>Background</h4>Panic disorder (PD) is a kind of mental illness characterized by the symptom of recurring panic attacks. Qiangzhifang (QZF) is a novel decoction developed by Professor Zhaojun Yan based on a unique system of syndrome differentiation and clinical experience. It has achieved remarkable results after long-term clinical practice, but its mechanism of action is still unclear. This study aims to use network pharmacology and molecular docking to explore the mechanism of QZF in the treatment of PD.<h4>Methods</h4>We used the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP), a literature search, and Encyclopedia of Traditional Chinese Medicine (ETCM) to find active ingredients and targets of QZF. We searched for PD targets in GeneCards, OnlAnnals of translational medicine1350https://www.ebi.ac.uk/biostudies/studies/S-EPMC8422112biostudies-literatureNetwork pharmacology study on the mechanism of Qiangzhifang in the treatment of panic disorder.PMC8422112Chu QJiang YLiu YLiu JYan ZZhao RSong ALiu PDong CShi HfalseNetwork pharmacology study on the mechanism of Qiangzhifang in the treatment of panic disorder.<h4>Background</h4>Panic disorder (PD) is a kind of mental illness characterized by the symptom of recurring panic attacks. Qiangzhifang (QZF) is a novel decoction developed by Professor Zhaojun Yan based on a unique system of syndrome differentiation and clinical experience. It has achieved remarkable results after long-term clinical practice, but its mechanism of action is still unclear. This study aims to use network pharmacology and molecular docking to explore the mechanism of QZF in the treatment of PD.<h4>Methods</h4>We used the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP), a literature search, and Encyclopedia of Traditional Chinese Medicine (ETCM) to find active ingredients and targets of QZF. We searched for PD targets in GeneCards, Onl2021-01-01T00:00:00Z2021 Aug2026-05-09T00:19:01.038Z2022-02-11T11:07:43.301ZS-EPMC84221123453248710.21037/atm-21-4090