{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Minkus CL"],"funding":["NEI NIH HHS"],"pagination":["200-209"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8429526"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["229"],"pubmed_abstract":["<h4>Purpose</h4>To determine the incidence of and predictive factors for cataract in intermediate uveitis.<h4>Design</h4>Retrospective cohort study.<h4>Methods</h4>Patients were identified from the Systemic Immunosuppressive Therapy for Eye Diseases Cohort Study, in which medical records were reviewed to determine demographic and clinical data of every eye/patient at every visit at 5 participating US tertiary care uveitis centers. The primary outcome was development of vision-compromising cataract as defined by a decrease in visual acuity to 20/40 or less, or requiring cataract surgery. Survival analysis assessed visually defined cataract to avoid bias due to timing of surgery vis-à-vis inflammatory status.<h4>Results</h4>Among 2,190 eyes of 1,302 patients with intermediate uveitis, the cu"],"journal":["American journal of ophthalmology"],"pubmed_title":["Risk of Cataract in Intermediate Uveitis."],"pmcid":["PMC8429526"],"funding_grant_id":["R21 EY026717","R01 EY014943"],"pubmed_authors":["Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Cohort Study Research Group","Foster CS","Payal AR","Minkus CL","Thorne JE","Rosenbaum JT","Sen HN","Buchanich JM","Begum H","Kacmaz RO","Kempen JH","Bhatt NP","Dreger KA","Pistilli M","Jabs DA","Levy-Clarke GA","Suhler EB","Nussenblatt RB","Fitzgerald TD"],"additional_accession":[]},"is_claimable":false,"name":"Risk of Cataract in Intermediate Uveitis.","description":"<h4>Purpose</h4>To determine the incidence of and predictive factors for cataract in intermediate uveitis.<h4>Design</h4>Retrospective cohort study.<h4>Methods</h4>Patients were identified from the Systemic Immunosuppressive Therapy for Eye Diseases Cohort Study, in which medical records were reviewed to determine demographic and clinical data of every eye/patient at every visit at 5 participating US tertiary care uveitis centers. The primary outcome was development of vision-compromising cataract as defined by a decrease in visual acuity to 20/40 or less, or requiring cataract surgery. Survival analysis assessed visually defined cataract to avoid bias due to timing of surgery vis-à-vis inflammatory status.<h4>Results</h4>Among 2,190 eyes of 1,302 patients with intermediate uveitis, the cu","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Sep","modification":"2025-04-04T09:37:18.044Z","creation":"2025-04-04T09:37:18.044Z"},"accession":"S-EPMC8429526","cross_references":{"pubmed":["33713679"],"doi":["10.1016/j.ajo.2021.02.032"]}}