biostudies-literatureUnknown11(4)Chugh ADepartment of Science and Technology, Ministry of Science and Technology, India<h4>Introduction</h4>TMJ ankylosis (TMJa) management by arthroplasty alone fails to address the deformity and the compromised airway. Distraction osteogenesis (DO) can offer a pragmatic solution to TMJa. The aim of the study was to generate evidence towards the role of DO in TMJa, evaluate its efficiency and develop an algorithm for use of DO in TMJa.<h4>Material and methods</h4>The research question was formulated using the PICOS statement for reporting guidelines in systematic reviews, where the efficiency of DO was evaluated in terms of mouth opening, correction of facial deformity and asymmetry, airway correction, and its long term effects.<h4>Results</h4>1130 articles reported DO as a treatment modality for TMJ ankylosis, of which 32 prospective studies, 16 retrospective and 2 RCTs weJournal of oral biology and craniofacial research581-595https://www.ebi.ac.uk/biostudies/studies/S-EPMC8435699biostudies-literatureA systematic review on the outcome of distraction osteogenesis in TMJ ankylosis.PMC8435699Mehrotra DChugh AYadav PKfalseA systematic review on the outcome of distraction osteogenesis in TMJ ankylosis.<h4>Introduction</h4>TMJ ankylosis (TMJa) management by arthroplasty alone fails to address the deformity and the compromised airway. Distraction osteogenesis (DO) can offer a pragmatic solution to TMJa. The aim of the study was to generate evidence towards the role of DO in TMJa, evaluate its efficiency and develop an algorithm for use of DO in TMJa.<h4>Material and methods</h4>The research question was formulated using the PICOS statement for reporting guidelines in systematic reviews, where the efficiency of DO was evaluated in terms of mouth opening, correction of facial deformity and asymmetry, airway correction, and its long term effects.<h4>Results</h4>1130 articles reported DO as a treatment modality for TMJ ankylosis, of which 32 prospective studies, 16 retrospective and 2 RCTs we2021-01-01T00:00:00Z2021 Oct-Dec2025-08-12T03:04:43.099Z2022-02-11T11:06:32.167ZS-EPMC84356993454057810.1016/j.jobcr.2021.07.007