{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8"],"submitter":["Rui M"],"pubmed_abstract":["<b>Background:</b> Several drugs currently are available for the treatment of Crohn's disease, including non-biological agents such as anti-inflammatory agents, steroids, immunosuppressive agents, and biologic agents such as anti-tumor necrosis factor (TNF), anti-α4β7 integrin, anti-alpha-4 integrin and anti-interleukin 12/23. However, the choice of treatments for induction and maintenance is still a challenge. The relevant comparison between non-biologic agents and biologic agents is few. In our research, we aimed to help making decisions, as well as providing clinicians and patients with medication references. <b>Methods:</b> We searched MEDLINE, Embase, and the Cochrane Central Register of controlled trials for relevant randomized controlled trials published through to July 2020 and sys"],"journal":["Frontiers in medicine"],"pagination":["679258"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8440847"],"repository":["biostudies-literature"],"pubmed_title":["Will the Inducing and Maintaining Remission of Non-biological Agents and Biological Agents Differ for Crohn's Disease? The Evidence From the Network Meta-Analysis."],"pmcid":["PMC8440847"],"pubmed_authors":["Ma A","Li H","Meng R","Shi F","Rui M","Shang Y","Wang Y","Fei Z"],"additional_accession":[]},"is_claimable":false,"name":"Will the Inducing and Maintaining Remission of Non-biological Agents and Biological Agents Differ for Crohn's Disease? The Evidence From the Network Meta-Analysis.","description":"<b>Background:</b> Several drugs currently are available for the treatment of Crohn's disease, including non-biological agents such as anti-inflammatory agents, steroids, immunosuppressive agents, and biologic agents such as anti-tumor necrosis factor (TNF), anti-α4β7 integrin, anti-alpha-4 integrin and anti-interleukin 12/23. However, the choice of treatments for induction and maintenance is still a challenge. The relevant comparison between non-biologic agents and biologic agents is few. In our research, we aimed to help making decisions, as well as providing clinicians and patients with medication references. <b>Methods:</b> We searched MEDLINE, Embase, and the Cochrane Central Register of controlled trials for relevant randomized controlled trials published through to July 2020 and sys","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021","modification":"2025-05-18T11:43:54.759Z","creation":"2025-05-18T11:43:54.759Z"},"accession":"S-EPMC8440847","cross_references":{"pubmed":["34540859"],"doi":["10.3389/fmed.2021.679258"]}}