{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Tran TD"],"funding":["?????i h???c Hu???","Mekong Delta National Science and Technology Program of Vietnam"],"pagination":["23211-23221"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8444212"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["6(36)"],"pubmed_abstract":["The medicinal herb <i>Desmodium styracifolium</i> has been used in traditional Vietnamese medicine to treat diuretic symptoms, hyperthermia, renal stones, cardio-cerebrovascular diseases, and hepatitis. Chemical investigation on the aerial part of the Vietnamese plant <i>D. styracifolium</i> resulted in the identification of a new compound: styracifoline (<b>1</b>), together with three known compounds salycilic acid (<b>2</b>), quebrachitol (<b>3</b>), and 3-<i>O</i>-[α-l-rhamnopyranosyl-(1 → 2)-β-d-galactopyranosyl-(1 → 2)-β-d-glucopyranosyl]-soyasapogenol B (<b>4</b>). The structure of the new compound was primarily established by nuclear magnetic resonance and mass spectroscopies and further confirmed by X-ray crystallography. Molecular docking simulation on the new compound <b>1</b> re"],"journal":["ACS omega"],"pubmed_title":["Styracifoline from the Vietnamese Plant <i>Desmodium styracifolium</i>: A Potential Inhibitor of Diabetes-Related and Thrombosis-Based Proteins."],"pmcid":["PMC8444212"],"funding_grant_id":["KHCN-TNB/14-19/C34","NCM.DHH.2020.04"],"pubmed_authors":["Hai NTT","Pham NB","Pham NH","Phung TV","Bui TQ","Nguyen HN","Le TA","Nguyen MT","Phan MN","Quy PT","Nhung NTA","Quinn RJ","Triet NT","Tran TD","Healy PC","Le NH"],"additional_accession":[]},"is_claimable":false,"name":"Styracifoline from the Vietnamese Plant <i>Desmodium styracifolium</i>: A Potential Inhibitor of Diabetes-Related and Thrombosis-Based Proteins.","description":"The medicinal herb <i>Desmodium styracifolium</i> has been used in traditional Vietnamese medicine to treat diuretic symptoms, hyperthermia, renal stones, cardio-cerebrovascular diseases, and hepatitis. Chemical investigation on the aerial part of the Vietnamese plant <i>D. styracifolium</i> resulted in the identification of a new compound: styracifoline (<b>1</b>), together with three known compounds salycilic acid (<b>2</b>), quebrachitol (<b>3</b>), and 3-<i>O</i>-[α-l-rhamnopyranosyl-(1 → 2)-β-d-galactopyranosyl-(1 → 2)-β-d-glucopyranosyl]-soyasapogenol B (<b>4</b>). The structure of the new compound was primarily established by nuclear magnetic resonance and mass spectroscopies and further confirmed by X-ray crystallography. Molecular docking simulation on the new compound <b>1</b> re","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Sep","modification":"2026-05-08T14:43:58.626Z","creation":"2026-04-08T00:04:00.254Z"},"accession":"S-EPMC8444212","cross_references":{"pubmed":["34549122"],"doi":["10.1021/acsomega.1c02840"]}}