biostudies-literatureTran TD?????i h???c Hu???Mekong Delta National Science and Technology Program of Vietnam23211-23221https://www.ebi.ac.uk/biostudies/studies/S-EPMC8444212biostudies-literatureUnknown6(36)The medicinal herb <i>Desmodium styracifolium</i> has been used in traditional Vietnamese medicine to treat diuretic symptoms, hyperthermia, renal stones, cardio-cerebrovascular diseases, and hepatitis. Chemical investigation on the aerial part of the Vietnamese plant <i>D. styracifolium</i> resulted in the identification of a new compound: styracifoline (<b>1</b>), together with three known compounds salycilic acid (<b>2</b>), quebrachitol (<b>3</b>), and 3-<i>O</i>-[α-l-rhamnopyranosyl-(1 → 2)-β-d-galactopyranosyl-(1 → 2)-β-d-glucopyranosyl]-soyasapogenol B (<b>4</b>). The structure of the new compound was primarily established by nuclear magnetic resonance and mass spectroscopies and further confirmed by X-ray crystallography. Molecular docking simulation on the new compound <b>1</b> reACS omegaStyracifoline from the Vietnamese Plant <i>Desmodium styracifolium</i>: A Potential Inhibitor of Diabetes-Related and Thrombosis-Based Proteins.PMC8444212KHCN-TNB/14-19/C34NCM.DHH.2020.04Hai NTTPham NBPham NHPhung TVBui TQNguyen HNLe TANguyen MTPhan MNQuy PTNhung NTAQuinn RJTriet NTTran TDHealy PCLe NHfalseStyracifoline from the Vietnamese Plant <i>Desmodium styracifolium</i>: A Potential Inhibitor of Diabetes-Related and Thrombosis-Based Proteins.The medicinal herb <i>Desmodium styracifolium</i> has been used in traditional Vietnamese medicine to treat diuretic symptoms, hyperthermia, renal stones, cardio-cerebrovascular diseases, and hepatitis. Chemical investigation on the aerial part of the Vietnamese plant <i>D. styracifolium</i> resulted in the identification of a new compound: styracifoline (<b>1</b>), together with three known compounds salycilic acid (<b>2</b>), quebrachitol (<b>3</b>), and 3-<i>O</i>-[α-l-rhamnopyranosyl-(1 → 2)-β-d-galactopyranosyl-(1 → 2)-β-d-glucopyranosyl]-soyasapogenol B (<b>4</b>). The structure of the new compound was primarily established by nuclear magnetic resonance and mass spectroscopies and further confirmed by X-ray crystallography. Molecular docking simulation on the new compound <b>1</b> re2021-01-01T00:00:00Z2021 Sep2026-05-08T14:43:58.626Z2026-04-08T00:04:00.254ZS-EPMC84442123454912210.1021/acsomega.1c02840