biostudies-literatureUnknown13Han T<h4>Objectives</h4>We analyzed how the virus spreads to local communities, based on the results of an epidemiological investigation of a religious facility in which a large group of patients was infected. Furthermore, we report for the first time in South Korea that a domestic cat was infected with SARS-CoV-2.<h4>Methods</h4>An epidemiological investigation was conducted to investigate the group outbreak. In addition, to verify cat-cat or cat-human transmission, we monitored whether exposed cats or humans were infected. Next-generation sequencing (NGS) of the viral full-length genome test was conducted on the positive samples from both owners and the cats.<h4>Results</h4>Total number of SARS-CoV-2 cases rose from 78 individuals, who visited a religious facility who were involved in 42 transmitted cases in the community, either through close contact with household members (47.62%) or through a group outbreak (16.67%). We observed an infected cat as well as individuals to which they were exposed. However, neither-further-cat to cat nor cat to human transmission occurred.<h4>Conclusions</h4>COVID-19 can be transmitted from humans to animals under certain conditions. Therefore, monitoring and studying the transmission of COVID-19, a novel infectious disease, between humans and animals is necessary through the One Health approach.One health (Amsterdam, Netherlands)100328https://www.ebi.ac.uk/biostudies/studies/S-EPMC8445762biostudies-literatureManagement following the first confirmed case of SARS-CoV-2 in a domestic cat associated with a massive outbreak in South Korea.PMC8445762Jeong YLee SKim EHwang HKim ILee HKim JRyu BHan TLee WSong YfalseManagement following the first confirmed case of SARS-CoV-2 in a domestic cat associated with a massive outbreak in South Korea.<h4>Objectives</h4>We analyzed how the virus spreads to local communities, based on the results of an epidemiological investigation of a religious facility in which a large group of patients was infected. Furthermore, we report for the first time in South Korea that a domestic cat was infected with SARS-CoV-2.<h4>Methods</h4>An epidemiological investigation was conducted to investigate the group outbreak. In addition, to verify cat-cat or cat-human transmission, we monitored whether exposed cats or humans were infected. Next-generation sequencing (NGS) of the viral full-length genome test was conducted on the positive samples from both owners and the cats.<h4>Results</h4>Total number of SARS-CoV-2 cases rose from 78 individuals, who visited a religious facility who were involved in 42 transmitted cases in the community, either through close contact with household members (47.62%) or through a group outbreak (16.67%). We observed an infected cat as well as individuals to which they were exposed. However, neither-further-cat to cat nor cat to human transmission occurred.<h4>Conclusions</h4>COVID-19 can be transmitted from humans to animals under certain conditions. Therefore, monitoring and studying the transmission of COVID-19, a novel infectious disease, between humans and animals is necessary through the One Health approach.2021-01-01T00:00:00Z2021 Dec2025-04-22T09:40:53.851Z2024-12-04T08:20:13.774ZS-EPMC84457623454907710.1016/j.onehlt.2021.100328