{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["21(1)"],"submitter":["Dong W"],"pubmed_abstract":["<h4>Background</h4>Siraitia grosvenorii (binomial name Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang), also called Arhat Fruit or Monk's Fruit, is a dried ripe fruit belonging to the Cucurbitaceae Family. S. grosvenorii has a long history of being used for constipation treatment in folk medicine. However, there are few studies where the laxative effect, related mechanisms, and active constituents of S. grosvenorii were investigated. This research explores the relationship between the common components and the laxative effect of aqueous extracts of S. grosvenorii from different habitats in China.<h4>Methods</h4>The fingerprints of S. grosvenorii aqueous extracts from different habitats were established by HPLC. The constipation mice model was used to investigate the laxativ"],"journal":["BMC complementary medicine and therapies"],"pagination":["235"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8451111"],"repository":["biostudies-literature"],"pubmed_title":["Exploration of the profile-effect relationship of Siraitia grosvenorii aqueous extracts related to their laxative effect on the basis of gray correlation analysis."],"pmcid":["PMC8451111"],"pubmed_authors":["Dong W","Huang T","Wang Q","Jiang X","Zeng J"],"additional_accession":[]},"is_claimable":false,"name":"Exploration of the profile-effect relationship of Siraitia grosvenorii aqueous extracts related to their laxative effect on the basis of gray correlation analysis.","description":"<h4>Background</h4>Siraitia grosvenorii (binomial name Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang), also called Arhat Fruit or Monk's Fruit, is a dried ripe fruit belonging to the Cucurbitaceae Family. S. grosvenorii has a long history of being used for constipation treatment in folk medicine. However, there are few studies where the laxative effect, related mechanisms, and active constituents of S. grosvenorii were investigated. This research explores the relationship between the common components and the laxative effect of aqueous extracts of S. grosvenorii from different habitats in China.<h4>Methods</h4>The fingerprints of S. grosvenorii aqueous extracts from different habitats were established by HPLC. The constipation mice model was used to investigate the laxativ","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Sep","modification":"2025-04-04T14:53:09.924Z","creation":"2022-02-11T11:08:23.294Z"},"accession":"S-EPMC8451111","cross_references":{"pubmed":["34544411"],"doi":["10.1186/s12906-021-03388-x"]}}