{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Stoeck CT"],"funding":["Swiss National Science Foundation"],"pagination":["103"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8451129"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["23(1)"],"pubmed_abstract":["<h4>Background</h4>We examined the dynamic response of the myocardium to infarction in a longitudinal porcine study using relaxometry, functional as well as diffusion cardiovascular magnetic resonance (CMR). We sought to compare non contrast CMR methods like relaxometry and in-vivo diffusion to contrast enhanced imaging and investigate the link of microstructural and functional changes in the acute and chronically infarcted heart.<h4>Methods</h4>CMR was performed on five myocardial infarction pigs and four healthy controls. In the infarction group, measurements were obtained 2 weeks before 90 min occlusion of the left circumflex artery, 6 days after ischemia and at 5 as well as 9 weeks as chronic follow-up. The timing of measurements was replicated in the control cohort. Imaging consisted "],"journal":["Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance"],"pubmed_title":["Cardiovascular magnetic resonance imaging of functional and microstructural changes of the heart in a longitudinal pig model of acute to chronic myocardial infarction."],"pmcid":["PMC8451129"],"funding_grant_id":["320030","153014","CR23I3_166485","320030_153014","PZ00P2 174144","166485","174144"],"pubmed_authors":["von Deuster C","Polacin M","Fleischmann T","Kron M","Cesarovic N","Waschkies CF","Fuetterer M","Kozerke S","Stoeck CT","van Gorkum RJH","Weisskopf M"],"additional_accession":[]},"is_claimable":false,"name":"Cardiovascular magnetic resonance imaging of functional and microstructural changes of the heart in a longitudinal pig model of acute to chronic myocardial infarction.","description":"<h4>Background</h4>We examined the dynamic response of the myocardium to infarction in a longitudinal porcine study using relaxometry, functional as well as diffusion cardiovascular magnetic resonance (CMR). We sought to compare non contrast CMR methods like relaxometry and in-vivo diffusion to contrast enhanced imaging and investigate the link of microstructural and functional changes in the acute and chronically infarcted heart.<h4>Methods</h4>CMR was performed on five myocardial infarction pigs and four healthy controls. In the infarction group, measurements were obtained 2 weeks before 90 min occlusion of the left circumflex artery, 6 days after ischemia and at 5 as well as 9 weeks as chronic follow-up. The timing of measurements was replicated in the control cohort. Imaging consisted ","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Sep","modification":"2026-05-08T12:17:02.866Z","creation":"2022-02-11T11:08:12.433Z"},"accession":"S-EPMC8451129","cross_references":{"pubmed":["34538266"],"doi":["10.1186/s12968-021-00794-5"]}}