{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Tripp JC"],"funding":["Veterans Affairs Clinical Science Research and Development","CSRD VA"],"pagination":["920-928"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8454212"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(8)"],"pubmed_abstract":["<h4>Objective</h4>Patients with posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) are often not offered exposure therapy for PTSD due to concerns that symptoms may worsen. This study examined whether initiating exposure would cause exacerbation of PTSD, alcohol use, depression, or suicidal ideation (SI) among patients with PTSD/AUD participating in exposure therapy for PTSD.<h4>Method</h4>Veterans were randomized to either concurrent treatment of PTSD and substance use disorders using prolonged exposure (COPE) or seeking safety, a nonexposure intervention, and were included in this study if they had data to at least Session 5 available (n = 81). They completed measures of PTSD, alcohol use, and depression/SI symptom severity throughout treatment and posttreatment. The rel"],"journal":["Psychological trauma : theory, research, practice and policy"],"pubmed_title":["Does exposure exacerbate symptoms in veterans with PTSD and alcohol use disorder?"],"pmcid":["PMC8454212"],"funding_grant_id":["1I01CX000756","I01 CX000756"],"pubmed_authors":["Trim RS","Bryan CJ","Straus E","Davis BC","Lyons R","Norman SB","Tripp JC","Haller M","Hamblen JL"],"additional_accession":[]},"is_claimable":false,"name":"Does exposure exacerbate symptoms in veterans with PTSD and alcohol use disorder?","description":"<h4>Objective</h4>Patients with posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) are often not offered exposure therapy for PTSD due to concerns that symptoms may worsen. This study examined whether initiating exposure would cause exacerbation of PTSD, alcohol use, depression, or suicidal ideation (SI) among patients with PTSD/AUD participating in exposure therapy for PTSD.<h4>Method</h4>Veterans were randomized to either concurrent treatment of PTSD and substance use disorders using prolonged exposure (COPE) or seeking safety, a nonexposure intervention, and were included in this study if they had data to at least Session 5 available (n = 81). They completed measures of PTSD, alcohol use, and depression/SI symptom severity throughout treatment and posttreatment. The rel","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Nov","modification":"2025-04-04T22:33:47.19Z","creation":"2025-02-19T03:24:06.936Z"},"accession":"S-EPMC8454212","cross_references":{"pubmed":["32673006"],"doi":["10.1037/tra0000634"]}}