{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Johnson LF"],"funding":["Intramural NIH HHS","NCATS NIH HHS","NICHD NIH HHS","NCRR NIH HHS","NIDA NIH HHS","NIA NIH HHS","NIAID NIH HHS","NIMH NIH HHS","NIAAA NIH HHS","National Institutes of Health","NEI NIH HHS","NIMHD NIH HHS","NCI NIH HHS","NIGMS NIH HHS"],"pagination":["e25776"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8454679"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["24 Suppl 5"],"pubmed_abstract":["<h4>Introduction</h4>The third of the Joint United Nations Programme on HIV/AIDS (UNAIDS) 90-90-90 targets is to achieve a 90% rate of viral suppression (HIV viral load <1000 HIV-1 RNA copies/ml) in patients on antiretroviral treatment (ART) by 2020. However, some countries use different thresholds when reporting viral suppression, and there is thus a need for an adjustment to standardize estimates to the <1000 threshold. We aim to propose such an adjustment, to support consistent monitoring of progress towards the \"third 90\" target.<h4>Methods</h4>We considered three possible distributions for viral loads in ART patients: Weibull, Pareto and reverse Weibull (imposing an upper limit but no lower limit on the log scale). The models were fitted to data on viral load distributions in ART pati"],"journal":["Journal of the International AIDS Society"],"pubmed_title":["Achieving consistency in measures of HIV-1 viral suppression across countries: derivation of an adjustment based on international antiretroviral treatment cohort data."],"pmcid":["PMC8454679"],"funding_grant_id":["K01 AI131895","K24 DA000432","U01 AI038858","U01 AI069919","KL2 TR000421","U01 AI038855","R01 DA011602","R01 AA016893","U01 AI069923","U01 AI068636","U01 AA020790","U01 AI069924","U01 AI103401","U01 AI103408","UL1 TR000083","U01 AI068634","K23 EY013707","U10 EY008067","P30 AI027767","U01 AI096299","U54 GM133807","P30 AI027763","U01 AI031834","U01 AI034989","U01 AI103397","U01 AI037613","P30 AI036219","UM1 AI035043","U01 HD032632","F31 AI124794","UL1 TR000004","U01 AI035039","U24 AA020794","U01 AI103390","U54 AG062334","U01 AI042590","R01 CA165937","M01 RR000052","P30 AI050410","K01 AI093197","U10 EY008057","U01 AA013566","P30 AI027757","P30 AI110527","UL1 TR000454","N02CP55504","U01 AI034994","U01 AI035004","F31 DA037788","U01 AI034993","U01 AI037984","U10 EY008052","U01 AI035041","U01 AI035040","G12 MD007583","U01 AI035042","U01 AI069907","UL1 RR024131","P30 AI094189","R24 AI067039","R24 AI124872","U01 DA036935","R01 AG053100","K24 AI065298","N01 CP001004","UL1 TR002489","U01AI096299","KL2 TR002317","U01 AA026209","K01AI131895","R01 DA012568","P30 MH062246","U01 AI069911","U01 AI069918","U54 MD007587","Z01 CP010176","U01 AI069432","K24 AI118591","U01 AI069434"],"pubmed_authors":["Kariminia A","Trickey A","Yiannoutsos CT","Han WM","Hsiao NY","Johnson LF","Minga AK","Zhang L","Murenzi G","Ekouevi DK","Rebeiro PF","Pascom ARP","Althoff KN","Ross J","Marsh K"],"additional_accession":[]},"is_claimable":false,"name":"Achieving consistency in measures of HIV-1 viral suppression across countries: derivation of an adjustment based on international antiretroviral treatment cohort data.","description":"<h4>Introduction</h4>The third of the Joint United Nations Programme on HIV/AIDS (UNAIDS) 90-90-90 targets is to achieve a 90% rate of viral suppression (HIV viral load <1000 HIV-1 RNA copies/ml) in patients on antiretroviral treatment (ART) by 2020. However, some countries use different thresholds when reporting viral suppression, and there is thus a need for an adjustment to standardize estimates to the <1000 threshold. We aim to propose such an adjustment, to support consistent monitoring of progress towards the \"third 90\" target.<h4>Methods</h4>We considered three possible distributions for viral loads in ART patients: Weibull, Pareto and reverse Weibull (imposing an upper limit but no lower limit on the log scale). The models were fitted to data on viral load distributions in ART pati","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Sep","modification":"2026-07-16T11:16:01.501Z","creation":"2022-02-11T11:21:23.167Z"},"accession":"S-EPMC8454679","cross_references":{"pubmed":["34546623"],"doi":["10.1002/jia2.25776"]}}