biostudies-literatureUnknownZhu JNIDDK NIH HHSNCI NIH HHSNational Institutes of HealthIngram Cancer Professorship FundNIH HHSAssociations of coffee and tea consumption with lung cancer risk have been inconsistent, and most lung cancer cases investigated were smokers. Included in this study were over 1.1 million participants from 17 prospective cohorts. Cox regression analyses were conducted to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). Potential effect modifications by sex, smoking, race, cancer subtype and coffee type were assessed. After a median 8.6 years of follow-up, 20 280 incident lung cancer cases were identified. Compared with noncoffee and nontea consumption, HRs (95% CIs) associated with exclusive coffee drinkers (≥2 cups/d) among current, former and never smokers were 1.30 (1.15-1.47), 1.49 (1.27-1.74) and 1.35 (1.15-1.58), respectively. Corresponding HRs for exclusive tea drinkInternational journal of cancerhttps://www.ebi.ac.uk/biostudies/studies/S-EPMC8460087biostudies-literatureAssociations of coffee and tea consumption with lung cancer risk.PMC8460087R01 CA082729UM1 CA182910UM1 CA173640R03 CA183021P30 DK056341Willett WCLee JESugawara YYu DAbe SKKim JTakata YRothman NKoh WPPark YTomata YGao YTTsugane SKanemura SFreedman NDWhite EYoo KYPark SKRobien KYuan JMSmith-Warner SAShu XOInoue MRahman MSZheng WLi XSaito ESinha RZhu JTsuji ILazovich DLan QZhang XSawada NXiang YBBlot WJLoftfield EfalseAssociations of coffee and tea consumption with lung cancer risk.Associations of coffee and tea consumption with lung cancer risk have been inconsistent, and most lung cancer cases investigated were smokers. Included in this study were over 1.1 million participants from 17 prospective cohorts. Cox regression analyses were conducted to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). Potential effect modifications by sex, smoking, race, cancer subtype and coffee type were assessed. After a median 8.6 years of follow-up, 20 280 incident lung cancer cases were identified. Compared with noncoffee and nontea consumption, HRs (95% CIs) associated with exclusive coffee drinkers (≥2 cups/d) among current, former and never smokers were 1.30 (1.15-1.47), 1.49 (1.27-1.74) and 1.35 (1.15-1.58), respectively. Corresponding HRs for exclusive tea drink2020-01-01T00:00:00Z2020 Dec2025-04-03T21:30:27.081Z2025-04-03T21:30:27.081ZS-EPMC84600873332660910.1002/ijc.33445