biostudies-literatureGoldschmidt ABNIDDK NIH HHSNational Institute of Diabetes and Digestive and Kidney Diseases740-747https://www.ebi.ac.uk/biostudies/studies/S-EPMC8474017biostudies-literatureUnknown29(4)<h4>Objectives</h4>The aim of this study was to assess associations between loss of control (LOC) eating and health outcomes among adolescents undergoing metabolic and bariatric surgery.<h4>Methods</h4>A total of 234 adolescents were studied before and up to 6 years after surgery in a prospective, observational cohort design. Adolescents provided self-reports of LOC eating, pain severity, sleep quality, polycystic ovary syndrome, gastroesophageal reflux disease, and medication usage and objective measures of fasting glucose, serum insulin, glycohemoglobin A_1c , cholesterol, triglycerides, and blood pressure. χ² tests, Wilcoxon rank sums, and generalized linear mixed models were used to assess concurrent and prospective associations between LOC eating and health indicaObesity (Silver Spring, Md.)Loss of Control Eating and Health Indicators Over 6 Years in Adolescents Undergoing Metabolic and Bariatric Surgery.PMC8474017U01 DK072493R01-DK080020K23‐DK105234R01 DK080020K23-DK105234U01‐DK072493K23 DK105234UM1 DK072493R01‐DK080020U01-DK072493Khoury JCInge THJenkins TMMichalsky MPZeller MHMitchell JEBond DSGoldschmidt ABfalseLoss of Control Eating and Health Indicators Over 6 Years in Adolescents Undergoing Metabolic and Bariatric Surgery.<h4>Objectives</h4>The aim of this study was to assess associations between loss of control (LOC) eating and health outcomes among adolescents undergoing metabolic and bariatric surgery.<h4>Methods</h4>A total of 234 adolescents were studied before and up to 6 years after surgery in a prospective, observational cohort design. Adolescents provided self-reports of LOC eating, pain severity, sleep quality, polycystic ovary syndrome, gastroesophageal reflux disease, and medication usage and objective measures of fasting glucose, serum insulin, glycohemoglobin A_1c , cholesterol, triglycerides, and blood pressure. χ² tests, Wilcoxon rank sums, and generalized linear mixed models were used to assess concurrent and prospective associations between LOC eating and health indica2021-01-01T00:00:00Z2021 Apr2025-04-04T23:03:13.094Z2025-04-04T23:03:13.094ZS-EPMC84740173375938310.1002/oby.23126