biostudies-literatureChow MRNIDCD NIH HHS521-532https://www.ebi.ac.uk/biostudies/studies/S-EPMC8477665biostudies-literatureUnknown384(6)<h4>Background</h4>Bilateral vestibular hypofunction is associated with chronic disequilibrium, postural instability, and unsteady gait owing to failure of vestibular reflexes that stabilize the eyes, head, and body. A vestibular implant may be effective in alleviating symptoms.<h4>Methods</h4>Persons who had had ototoxic (7 participants) or idiopathic (1 participant) bilateral vestibular hypofunction for 2 to 23 years underwent unilateral implantation of a prosthesis that electrically stimulates the three semicircular canal branches of the vestibular nerve. Clinical outcomes included the score on the Bruininks-Oseretsky Test of Motor Proficiency balance subtest (range, 0 to 36, with higher scores indicating better balance), time to failure on the modified Romberg test (range, 0 to 30 secoThe New England journal of medicinePosture, Gait, Quality of Life, and Hearing with a Vestibular Implant.PMC8477665T32 DC000023R01 DC013536K23 DC018302Trevino Guajardo CValentin NSBoutros PJSun DQCarey JPSchoo DPBowditch SPGimmon YSchubert MCLane KEAyiotis AIChow MRWard BKRahman MAMorris BJDella Santina CCfalsePosture, Gait, Quality of Life, and Hearing with a Vestibular Implant.<h4>Background</h4>Bilateral vestibular hypofunction is associated with chronic disequilibrium, postural instability, and unsteady gait owing to failure of vestibular reflexes that stabilize the eyes, head, and body. A vestibular implant may be effective in alleviating symptoms.<h4>Methods</h4>Persons who had had ototoxic (7 participants) or idiopathic (1 participant) bilateral vestibular hypofunction for 2 to 23 years underwent unilateral implantation of a prosthesis that electrically stimulates the three semicircular canal branches of the vestibular nerve. Clinical outcomes included the score on the Bruininks-Oseretsky Test of Motor Proficiency balance subtest (range, 0 to 36, with higher scores indicating better balance), time to failure on the modified Romberg test (range, 0 to 30 seco2021-01-01T00:00:00Z2021 Feb2026-05-08T07:02:21.368Z2025-04-03T22:48:06.399ZS-EPMC84776653356719210.1056/NEJMoa202045710.1056/nejmoa2020457