{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16"],"submitter":["Hanbali A"],"funding":["King Faisal Specialist Hospital and Research Center"],"pubmed_abstract":["Background
Treating adolescents and young adults (AYA) patients with acute lymphoblastic leukemia (ALL) using pediatric-inspired protocols have shown improvement in outcomes. Most data available in the literature of such protocols is derived from well-controlled clinical trials. This report aims to provide a real-world experience from using a pediatric-inspired protocol in ALL-AYA population in larger number of patients treated at a national tertiary care referral center.Methods
Newly diagnosed Philadelphia negative ALL-AYA patients ages between 14 and 55 years of age were treated on an institutional protocol (AYA-15 protocol) adopted from a modified version of Children's Cancer Group (CCG) 1900 protocol. At the time of this publication, a total of 79 patients were treated "],"journal":["Leukemia research reports"],"pagination":["100270"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8488255"],"repository":["biostudies-literature"],"pubmed_title":["Improved survival in adolescents and young adults (AYA) patients aged 14-55 years with acute lymphoblastic leukemia using pediatric-inspired protocol - a retrospective analysis of a real-world experience in 79 of patients treated at a national tertiary care referral center."],"pmcid":["PMC8488255"],"pubmed_authors":["Shaheen M","Aljurf M","Alfraih F","Alshaibani A","Alsharif F","Ahmed SO","Chaudhri N","Alhayli S","Riash MA","Asif M","Hanbali A","Alahmari A","Alotaibi A","Deeba F","Rasheed W","Fakih RE","Almohareb F","Kotb A","Alzahrani H"],"additional_accession":[]},"is_claimable":false,"name":"Improved survival in adolescents and young adults (AYA) patients aged 14-55 years with acute lymphoblastic leukemia using pediatric-inspired protocol - a retrospective analysis of a real-world experience in 79 of patients treated at a national tertiary care referral center.","description":"Background
Treating adolescents and young adults (AYA) patients with acute lymphoblastic leukemia (ALL) using pediatric-inspired protocols have shown improvement in outcomes. Most data available in the literature of such protocols is derived from well-controlled clinical trials. This report aims to provide a real-world experience from using a pediatric-inspired protocol in ALL-AYA population in larger number of patients treated at a national tertiary care referral center.Methods
Newly diagnosed Philadelphia negative ALL-AYA patients ages between 14 and 55 years of age were treated on an institutional protocol (AYA-15 protocol) adopted from a modified version of Children's Cancer Group (CCG) 1900 protocol. At the time of this publication, a total of 79 patients were treated ","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021","modification":"2025-04-19T21:38:56.2Z","creation":"2022-02-11T12:01:24.817Z"},"accession":"S-EPMC8488255","cross_references":{"pubmed":["34631407"],"doi":["10.1016/j.lrr.2021.100270"]}}