{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Choi JH"],"funding":["Boramae Medical Center","Seoul Metropolitan Government-Seoul National University"],"pagination":["221-225"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8490186"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(3)"],"pubmed_abstract":["<h4>Objective</h4>To assess nocturnal hypokinesia using the Korean version of the Nocturnal Hypokinesia Questionnaire (NHQ-K) in Parkinson's disease (PD) patients across disease stages.<h4>Methods</h4>We developed the NHQ-K and performed questionnaire-based interviews with 108 PD patients from three referral hospitals. Clinical associations of nocturnal hypokinesia and its impact on health-related quality of life (HRQoL) were also analyzed.<h4>Results</h4>The NHQ-K showed acceptable internal consistency (0.83) and interrater reliability (0.95). Nocturnal hypokinesia significantly affected HRQoL in PD patients at both the early and advanced stages (adjusted p < 0.001). Increased severity of nocturnal hypokinesia was associated with dyskinesias, off-period disability, apathy, and anxious moo"],"journal":["Journal of movement disorders"],"pubmed_title":["Investigation of Nocturnal Hypokinesia and Health-Related Quality of Life in Parkinsonian Patients with the Korean Version of the Nocturnal Hypokinesia Questionnaire."],"pmcid":["PMC8490186"],"funding_grant_id":["03-2018-8"],"pubmed_authors":["Shin C","Ahn TB","Kim JM","Jeon B","Kim HJ","Yoo D","Choi JH","Woo KA","Im JH","Lee JY"],"additional_accession":[]},"is_claimable":false,"name":"Investigation of Nocturnal Hypokinesia and Health-Related Quality of Life in Parkinsonian Patients with the Korean Version of the Nocturnal Hypokinesia Questionnaire.","description":"<h4>Objective</h4>To assess nocturnal hypokinesia using the Korean version of the Nocturnal Hypokinesia Questionnaire (NHQ-K) in Parkinson's disease (PD) patients across disease stages.<h4>Methods</h4>We developed the NHQ-K and performed questionnaire-based interviews with 108 PD patients from three referral hospitals. Clinical associations of nocturnal hypokinesia and its impact on health-related quality of life (HRQoL) were also analyzed.<h4>Results</h4>The NHQ-K showed acceptable internal consistency (0.83) and interrater reliability (0.95). Nocturnal hypokinesia significantly affected HRQoL in PD patients at both the early and advanced stages (adjusted p < 0.001). Increased severity of nocturnal hypokinesia was associated with dyskinesias, off-period disability, apathy, and anxious moo","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Sep","modification":"2025-06-01T12:10:52.86Z","creation":"2022-02-11T12:06:30.266Z"},"accession":"S-EPMC8490186","cross_references":{"pubmed":["34030433"],"doi":["10.14802/jmd.20172"]}}