biostudies-literatureRoomaney RASouth African Medical Research Councile048676https://www.ebi.ac.uk/biostudies/studies/S-EPMC8496399biostudies-literatureUnknown11(10)<h4>Objectives</h4>To review prevalence studies of multimorbidity in South Africa to identify prevalence estimates, common disease clusters and factors associated with multimorbidity.<h4>Design</h4>Systematic review.<h4>Setting</h4>South Africa (general community and healthcare facilities).<h4>Data sources</h4>Articles were retrieved from electronic databases (PubMed, Web of Science, Scopus, CINAHL, Science Direct and JSTOR).<h4>Eligibility criteria</h4>Studies addressing the prevalence of multimorbidity in South Africa were eligible for inclusion. A systematic search was done in various databases up to December 2020. A risk of bias assessment was conducted for each article using a modified checklist.<h4>Study selection</h4>Two researchers independently screened titles and abstracts; assesBMJ openMultimorbidity in South Africa: a systematic review of prevalence studies.PMC8496399NATurawa EBPillay-van Wyk Vvan Wyk BRoomaney RAfalseMultimorbidity in South Africa: a systematic review of prevalence studies.<h4>Objectives</h4>To review prevalence studies of multimorbidity in South Africa to identify prevalence estimates, common disease clusters and factors associated with multimorbidity.<h4>Design</h4>Systematic review.<h4>Setting</h4>South Africa (general community and healthcare facilities).<h4>Data sources</h4>Articles were retrieved from electronic databases (PubMed, Web of Science, Scopus, CINAHL, Science Direct and JSTOR).<h4>Eligibility criteria</h4>Studies addressing the prevalence of multimorbidity in South Africa were eligible for inclusion. A systematic search was done in various databases up to December 2020. A risk of bias assessment was conducted for each article using a modified checklist.<h4>Study selection</h4>Two researchers independently screened titles and abstracts; asses2021-01-01T00:00:00Z2021 Oct2025-04-26T10:14:38.421Z2025-04-06T13:14:41.054ZS-EPMC84963993461567510.1136/bmjopen-2021-048676