{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kusakabe M"],"funding":["Scientific Research C","Scientific Research B","Early-Career Scientists from the Japan Society for the Promotion of Science","NVIDIA Corporation provided support to Jason Lin in the form of hardware devices","Grant-in-Aids for Scientific Research on Innovative Areas","The SAPOIN strategic elevation of basic scientific research initiative from the Ministry of Economy, Trade and Industry of Japan"],"pagination":["e12247"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8496461"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9"],"pubmed_abstract":["Despite the benefit of early cancer screening, Japan has one of the lowest cancer screening rates among developed countries, possibly due to there being a lack of \"a good test\" that can provide sufficient levels of test sensitivity and accuracy without a large price tag. As a number of essential and trace elements have been intimately connected to the oncogenesis of cancer, Metallobalance, a recent development in elemental analysis utilizing the technique of inductively coupled plasma mass spectrometry has been developed and tested as a robust method for arrayed cancer risk screening. We have conducted case-control epidemiological studies in the prefecture of Chiba, in the Greater Tokyo Area, and sought to determine both Metallobalance screening's effectiveness for predicting pan-cancer ou"],"journal":["PeerJ"],"pubmed_title":["Elemental analysis by Metallobalance provides a complementary support layer over existing blood biochemistry panel-based cancer risk assessment."],"pmcid":["PMC8496461"],"funding_grant_id":["221S0001","JP17K15047","JP20H03540","21K15072","16H06277","JP20K10440"],"pubmed_authors":["Nagase H","Kusakabe M","Nakamura Y","Sato M","Lin J","Mikami H"],"additional_accession":[]},"is_claimable":false,"name":"Elemental analysis by Metallobalance provides a complementary support layer over existing blood biochemistry panel-based cancer risk assessment.","description":"Despite the benefit of early cancer screening, Japan has one of the lowest cancer screening rates among developed countries, possibly due to there being a lack of \"a good test\" that can provide sufficient levels of test sensitivity and accuracy without a large price tag. As a number of essential and trace elements have been intimately connected to the oncogenesis of cancer, Metallobalance, a recent development in elemental analysis utilizing the technique of inductively coupled plasma mass spectrometry has been developed and tested as a robust method for arrayed cancer risk screening. We have conducted case-control epidemiological studies in the prefecture of Chiba, in the Greater Tokyo Area, and sought to determine both Metallobalance screening's effectiveness for predicting pan-cancer ou","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021","modification":"2025-06-01T02:38:29.789Z","creation":"2025-06-01T02:38:29.789Z"},"accession":"S-EPMC8496461","cross_references":{"pubmed":["34707935"],"doi":["10.7717/peerj.12247"]}}