biostudies-literaturePeng XMinistry of Education - Singapore (MOE)Ministry of Education - Singapore5895https://www.ebi.ac.uk/biostudies/studies/S-EPMC8501084biostudies-literatureUnknown12(1)Creating atomically precise quantum architectures with high digital fidelity and desired quantum states is an important goal in a new era of quantum technology. The strategy of creating these quantum nanostructures mainly relies on atom-by-atom, molecule-by-molecule manipulation or molecular assembly through non-covalent interactions, which thus lack sufficient chemical robustness required for on-chip quantum device operation at elevated temperature. Here, we report a bottom-up synthesis of covalently linked organic quantum corrals (OQCs) with atomic precision to induce the formation of topology-controlled quantum resonance states, arising from a collective interference of scattered electron waves inside the quantum nanocavities. Individual OQCs host a series of atomic orbital-like resonanNature communicationsVisualizing designer quantum states in stable macrocycle quantum corrals.PMC8501084R-143-000-B58-114MOE2019-T2-2-044Peng XWu JMahalingam HJelinek PChi CSu JDong SMutombo PTelychko MNg PWRodin ALu JSong SLyu PfalseVisualizing designer quantum states in stable macrocycle quantum corrals.Creating atomically precise quantum architectures with high digital fidelity and desired quantum states is an important goal in a new era of quantum technology. The strategy of creating these quantum nanostructures mainly relies on atom-by-atom, molecule-by-molecule manipulation or molecular assembly through non-covalent interactions, which thus lack sufficient chemical robustness required for on-chip quantum device operation at elevated temperature. Here, we report a bottom-up synthesis of covalently linked organic quantum corrals (OQCs) with atomic precision to induce the formation of topology-controlled quantum resonance states, arising from a collective interference of scattered electron waves inside the quantum nanocavities. Individual OQCs host a series of atomic orbital-like resonan2021-01-01T00:00:00Z2021 Oct2025-04-22T07:56:00.217Z2025-04-05T22:19:57.095ZS-EPMC85010843462554210.1038/s41467-021-26198-8