biostudies-literatureUnknown12Li QNational Key Research and Development Program of China<b>Background:</b> Acute kidney injury (AKI) is a common complication after coronary angiography (CAG) and associated with heart failure (HF). Left ventricular (LV) remodeling is a vital process in the progression of HF. However, few studies investigate the relationship between AKI and LV remodeling. <b>Methods:</b> We included consecutive patients undergoing CAG from January 2007 to December 2018 at Guangdong Provincial People's Hospital (NCT04407936). AKI was defined as an absolute increase in serum creatinine (Scr) of ≥ 0.3mg/dl or a ≥ 50% increase in Scr from baseline within the first 48-72 h after the procedure. LV remodeling was defined as: (1) an absolute decrease in left ventricular ejection fraction (LVEF) of ≥ 10% compared to baseline, or (2) a follow-up LVEF < 40%. Univariate anFrontiers in physiology744735https://www.ebi.ac.uk/biostudies/studies/S-EPMC8502848biostudies-literatureAcute Kidney Injury Increase Risk of Left Ventricular Remodeling: A Cohort of 1,573 Patients.PMC8502848Li HLiu JLiu LShi SWang BChen JHuang HChen LLi QYing MLiu YHuang ZLai WChen WChen SfalseAcute Kidney Injury Increase Risk of Left Ventricular Remodeling: A Cohort of 1,573 Patients.<b>Background:</b> Acute kidney injury (AKI) is a common complication after coronary angiography (CAG) and associated with heart failure (HF). Left ventricular (LV) remodeling is a vital process in the progression of HF. However, few studies investigate the relationship between AKI and LV remodeling. <b>Methods:</b> We included consecutive patients undergoing CAG from January 2007 to December 2018 at Guangdong Provincial People's Hospital (NCT04407936). AKI was defined as an absolute increase in serum creatinine (Scr) of ≥ 0.3mg/dl or a ≥ 50% increase in Scr from baseline within the first 48-72 h after the procedure. LV remodeling was defined as: (1) an absolute decrease in left ventricular ejection fraction (LVEF) of ≥ 10% compared to baseline, or (2) a follow-up LVEF < 40%. Univariate an2021-01-01T00:00:00Z20212026-05-09T02:06:46.676Z2022-02-11T12:12:07.838ZS-EPMC85028483464616210.3389/fphys.2021.744735