biostudies-literatureUnknown39(9)Quhal FMedical University of Vienna<h4>Purpose</h4>To investigate the prognostic value of preoperative serum albumin to globulin ratio (AGR) in patients with non-muscle-invasive bladder cancer (NMIBC) treated with transurethral resection of bladder tumor (TURB) with or without intravesical therapy (IVT).<h4>Materials and methods</h4>We retrospectively reviewed 1,096 consecutive patients with NMIBC. Levels of albumin and globulin were obtained before TURB and used to calculate the preoperative AGR level. Multivariable Cox regression analyses were performed to assess the prognostic effect of preoperative AGR on oncologic outcomes. Subgroup analyses were performed in patients based on the European Association of Urology (EAU) risk groups for NMIBC.<h4>Results</h4>Low AGR levels were observed in 389 (35.5%) patients. The medianWorld journal of urology3345-3352https://www.ebi.ac.uk/biostudies/studies/S-EPMC8510920biostudies-literaturePrognostic value of albumin to globulin ratio in non-muscle-invasive bladder cancer.PMC8510920Rink MRoupret MSchuettfort VMAbufaraj MMori KQuhal FShariat SFKarakiewicz PILaukhtina EEnikeev DPradere BMostafaei HSari Motlagh RfalsePrognostic value of albumin to globulin ratio in non-muscle-invasive bladder cancer.<h4>Purpose</h4>To investigate the prognostic value of preoperative serum albumin to globulin ratio (AGR) in patients with non-muscle-invasive bladder cancer (NMIBC) treated with transurethral resection of bladder tumor (TURB) with or without intravesical therapy (IVT).<h4>Materials and methods</h4>We retrospectively reviewed 1,096 consecutive patients with NMIBC. Levels of albumin and globulin were obtained before TURB and used to calculate the preoperative AGR level. Multivariable Cox regression analyses were performed to assess the prognostic effect of preoperative AGR on oncologic outcomes. Subgroup analyses were performed in patients based on the European Association of Urology (EAU) risk groups for NMIBC.<h4>Results</h4>Low AGR levels were observed in 389 (35.5%) patients. The median2021-01-01T00:00:00Z2021 Sep2025-04-21T17:42:53.197Z2025-04-21T17:42:53.197ZS-EPMC85109203349684110.1007/s00345-020-03586-1