{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Chang Y"],"funding":["NIAID NIH HHS","National Institutes of Health","NIGMS NIH HHS"],"pagination":["1024-1033"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8510993"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["29(11)"],"pubmed_abstract":["The bacterial flagellar motor, a remarkable rotary machine, can rapidly switch between counterclockwise (CCW) and clockwise (CW) rotational directions to control the migration behavior of the bacterial cell. The flagellar motor consists of a bidirectional spinning rotor surrounded by torque-generating stator units. Recent high-resolution in vitro and in situ structural studies have revealed stunning details of the individual components of the flagellar motor and their interactions in both the CCW and CW senses. In this review, we discuss these structures and their implications for understanding the molecular mechanisms underlying flagellar rotation and switching."],"journal":["Trends in microbiology"],"pubmed_title":["Structural basis of bacterial flagellar motor rotation and switching."],"pmcid":["PMC8510993"],"funding_grant_id":["R01 AI132818","R01 GM107629","R01 AI087946"],"pubmed_authors":["Liu J","Carroll BL","Chang Y"],"additional_accession":[]},"is_claimable":false,"name":"Structural basis of bacterial flagellar motor rotation and switching.","description":"The bacterial flagellar motor, a remarkable rotary machine, can rapidly switch between counterclockwise (CCW) and clockwise (CW) rotational directions to control the migration behavior of the bacterial cell. The flagellar motor consists of a bidirectional spinning rotor surrounded by torque-generating stator units. Recent high-resolution in vitro and in situ structural studies have revealed stunning details of the individual components of the flagellar motor and their interactions in both the CCW and CW senses. In this review, we discuss these structures and their implications for understanding the molecular mechanisms underlying flagellar rotation and switching.","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Nov","modification":"2025-04-04T22:33:41.283Z","creation":"2025-02-19T03:24:01.145Z"},"accession":"S-EPMC8510993","cross_references":{"pubmed":["33865677"],"doi":["10.1016/j.tim.2021.03.009"]}}