{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Gunnlaugsson S"],"funding":["National Center for Advancing Translational Sciences","National Center for Research Resources","Genentech","NCATS NIH HHS","NIAID NIH HHS","NIEHS NIH HHS","NHLBI NIH HHS","National Institutes of Health","Harvard University","Harvard Catalyst","Novartis"],"pagination":["3679-3685.e1"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8511301"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9(10)"],"pubmed_abstract":["<h4>Background</h4>Inner-city children are disproportionately affected by asthma and sleep-disordered breathing (SDB). However, little is known about the association of SDB symptoms with asthma morbidity in this vulnerable population.<h4>Objective</h4>Assess the relationship between snoring frequency and asthma morbidity.<h4>Methods</h4>This study was part of the School Inner-City Asthma Study, a longitudinal prospective cohort study of children with persistent asthma who attended schools in the Northeast United States from 2008 to 2013. Participants had baseline assessments of asthma symptoms, snoring, and allergy status. Caregivers completed quarterly surveys for 12 months on symptoms of asthma, snoring, and health care outcomes. Snoring frequency (non-, rare-, sometimes-, habitual-snoring) and its relationship with asthma symptoms and asthma morbidity were assessed by mixed-effects models.<h4>Results</h4>There were 1186 observations from 339 subjects. Mean age was 7.9 years; roughly half were male, and most were of minority race. Half were overweight or obese, and 65.5% had atopy. At initial snoring assessment, 24.8% reported habitual snoring, but report of snoring frequency varied over the study period. Multivariate analyses revealed increased odds of maximum asthma symptom days for habitual snoring compared with nonsnoring (1.58; 95% CI, 1.19-2.10; P < .002) and all other snoring categories. Habitual snoring was associated with greater odds of health care utilization (incidence rate ratio, 1.72; 95% CI, 1.10-2.69; P = .02) and worse asthma control (odds ratio, 1.49; 95% CI, 1.05-2.11; P = .03) compared with nonsnoring.<h4>Conclusions</h4>Snoring is common among inner-city school-age children with asthma, and habitual snoring is associated with increased asthma symptom burden and health care utilization."],"journal":["The journal of allergy and clinical immunology. In practice"],"pubmed_title":["Associations of Snoring and Asthma Morbidity in the School Inner-City Asthma Study."],"pmcid":["PMC8511301"],"funding_grant_id":["R01 AI073964","F32 HL124919","U01 AI110397","K24 AI106822","F32 HL124919-01","UL1 TR001102","U01 AI 110397","3 U01 AI110397-02S1","K23 AI123517","R01030100","R01 AI 073964","R01 ES030100","K24 AI 106822","R01 HL137192","R01HL137192"],"pubmed_authors":["Abul MH","Wright L","Petty CR","Gaffin JM","Permaul P","Gold DR","Phipatanakul W","Gunnlaugsson S"],"additional_accession":[]},"is_claimable":false,"name":"Associations of Snoring and Asthma Morbidity in the School Inner-City Asthma Study.","description":"<h4>Background</h4>Inner-city children are disproportionately affected by asthma and sleep-disordered breathing (SDB). However, little is known about the association of SDB symptoms with asthma morbidity in this vulnerable population.<h4>Objective</h4>Assess the relationship between snoring frequency and asthma morbidity.<h4>Methods</h4>This study was part of the School Inner-City Asthma Study, a longitudinal prospective cohort study of children with persistent asthma who attended schools in the Northeast United States from 2008 to 2013. Participants had baseline assessments of asthma symptoms, snoring, and allergy status. Caregivers completed quarterly surveys for 12 months on symptoms of asthma, snoring, and health care outcomes. Snoring frequency (non-, rare-, sometimes-, habitual-snoring) and its relationship with asthma symptoms and asthma morbidity were assessed by mixed-effects models.<h4>Results</h4>There were 1186 observations from 339 subjects. Mean age was 7.9 years; roughly half were male, and most were of minority race. Half were overweight or obese, and 65.5% had atopy. At initial snoring assessment, 24.8% reported habitual snoring, but report of snoring frequency varied over the study period. Multivariate analyses revealed increased odds of maximum asthma symptom days for habitual snoring compared with nonsnoring (1.58; 95% CI, 1.19-2.10; P < .002) and all other snoring categories. Habitual snoring was associated with greater odds of health care utilization (incidence rate ratio, 1.72; 95% CI, 1.10-2.69; P = .02) and worse asthma control (odds ratio, 1.49; 95% CI, 1.05-2.11; P = .03) compared with nonsnoring.<h4>Conclusions</h4>Snoring is common among inner-city school-age children with asthma, and habitual snoring is associated with increased asthma symptom burden and health care utilization.","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Oct","modification":"2025-04-04T10:27:27.752Z","creation":"2025-04-04T10:27:27.752Z"},"accession":"S-EPMC8511301","cross_references":{"pubmed":["34102347"],"doi":["10.1016/j.jaip.2021.05.022"]}}