{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(9)"],"submitter":["Anderson E"],"pubmed_abstract":["<h4>Background</h4>Focal treatment for prostate cancer (PCa) is a hybrid approach combining ablative treatment of the involved prostate gland and continued active surveillance (AS) of the unaffected gland. Low dose-rate (LDR) brachytherapy can be used as a lesion-targeted focal therapy, however, further studies are required to support its use. The aim of this study is to evaluate the dosimetry, toxicity and oncological outcomes of men receiving lesion-targeted focal LDR brachytherapy for low to intermediate risk PCa.<h4>Methods</h4>This is a retrospective cohort study of 26 men with unifocal, low to intermediate grade PCa diagnosed on a combination of multiparametric-magnetic resonance imaging (mp-MRI) and targeted plus template transperineal (TP) biopsy, who received focal LDR brachythera"],"journal":["Translational andrology and urology"],"pagination":["3591-3603"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8511546"],"repository":["biostudies-literature"],"pubmed_title":["Focal low dose-rate brachytherapy for low to intermediate risk prostate cancer: preliminary experience at an Australian institution."],"pmcid":["PMC8511546"],"pubmed_authors":["Ryan A","Smyth LML","Anderson E","Grummet J","See AW","Lawrentschuk N","O'Sullivan R"],"additional_accession":[]},"is_claimable":false,"name":"Focal low dose-rate brachytherapy for low to intermediate risk prostate cancer: preliminary experience at an Australian institution.","description":"<h4>Background</h4>Focal treatment for prostate cancer (PCa) is a hybrid approach combining ablative treatment of the involved prostate gland and continued active surveillance (AS) of the unaffected gland. Low dose-rate (LDR) brachytherapy can be used as a lesion-targeted focal therapy, however, further studies are required to support its use. The aim of this study is to evaluate the dosimetry, toxicity and oncological outcomes of men receiving lesion-targeted focal LDR brachytherapy for low to intermediate risk PCa.<h4>Methods</h4>This is a retrospective cohort study of 26 men with unifocal, low to intermediate grade PCa diagnosed on a combination of multiparametric-magnetic resonance imaging (mp-MRI) and targeted plus template transperineal (TP) biopsy, who received focal LDR brachythera","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Sep","modification":"2025-04-04T09:37:34.434Z","creation":"2025-04-04T09:37:34.434Z"},"accession":"S-EPMC8511546","cross_references":{"pubmed":["34733655"],"doi":["10.21037/tau-21-508"]}}