{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Furuya T"],"funding":["ministry of education, culture, sports, science and technology"],"pagination":["1265-1277"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8514375"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["134(6)"],"pubmed_abstract":["Dual-specificity tyrosine phosphorylation-regulated kinases (DYRKs) are activated via the auto-phosphorylation of conserved tyrosine residues in their activation loop during protein translation, and they then phosphorylate serine/threonine residues on substrates. The DYRK family is widely conserved in eukaryotes and is composed of six subgroups. In plant lineages, DYRK homologs are classified into four subgroups, DYRK2s, yet another kinase1s, pre-mRNA processing factor 4 kinases, and DYRKPs. Only the DYRKP subgroup is plant-specific and has been identified in a wide array of plant lineages, including land plants and green algae. It has been suggested that in Arabidopsis thaliana DYRKPs are involved in the regulation of centripetal nuclear positioning induced by dark light conditions. Howev"],"journal":["Journal of plant research"],"pubmed_title":["A plant-specific DYRK kinase DYRKP coordinates cell morphology in Marchantia polymorpha."],"pmcid":["PMC8514375"],"funding_grant_id":["251113009","17K07753","16H04805","20K15813","19H05675","19H05672","25113001","25113002","19K21189"],"pubmed_authors":["Kajikawa M","Furuya T","Fukuzawa H","Kohchi T","Tsukaya H","Shinkawa H","Nishihama R"],"additional_accession":[]},"is_claimable":false,"name":"A plant-specific DYRK kinase DYRKP coordinates cell morphology in Marchantia polymorpha.","description":"Dual-specificity tyrosine phosphorylation-regulated kinases (DYRKs) are activated via the auto-phosphorylation of conserved tyrosine residues in their activation loop during protein translation, and they then phosphorylate serine/threonine residues on substrates. The DYRK family is widely conserved in eukaryotes and is composed of six subgroups. In plant lineages, DYRK homologs are classified into four subgroups, DYRK2s, yet another kinase1s, pre-mRNA processing factor 4 kinases, and DYRKPs. Only the DYRKP subgroup is plant-specific and has been identified in a wide array of plant lineages, including land plants and green algae. It has been suggested that in Arabidopsis thaliana DYRKPs are involved in the regulation of centripetal nuclear positioning induced by dark light conditions. Howev","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Nov","modification":"2025-04-04T19:11:14.982Z","creation":"2025-04-04T19:11:14.982Z"},"accession":"S-EPMC8514375","cross_references":{"pubmed":["34549353"],"doi":["10.1007/s10265-021-01345-w"]}}