biostudies-literatureUnknown11(10)Falk RS<h4>Purpose</h4>The Oslo Ischaemia Study was designed to investigate the prevalence and predictors of silent coronary disease in Norwegian middle-aged men, specifically validating exercise electrocardiography (ECG) findings compared with angiography. The study has been important in investigating long-term predictors of cardiovascular morbidity and mortality, as well as investigating a broad spectrum of epidemiological and public health perspectives.<h4>Participants</h4>In 1972-1975, 2014 healthy men, 40-59 years old, were enrolled in the study. Comprehensive clinical examination included an ECG-monitored exercise test at baseline and follow-ups. The cohort has been re-examined four times during 20 years. Linkage to health records and national health registries has ensured complete endpointBMJ opene049111https://www.ebi.ac.uk/biostudies/studies/S-EPMC8515426biostudies-literatureThe Oslo Ischaemia Study: cohort profile.PMC8515426Stavem KKjeldsen SEErikssen GLiestol KSandvik LSkretteberg PTHeir TMariampillai JEThaulow EBjornholt JVErikssen JEBodegard JGjesdal KPrestgaard EEGrundvold IFalk RSRobsahm TEEngeseth KfalseThe Oslo Ischaemia Study: cohort profile.<h4>Purpose</h4>The Oslo Ischaemia Study was designed to investigate the prevalence and predictors of silent coronary disease in Norwegian middle-aged men, specifically validating exercise electrocardiography (ECG) findings compared with angiography. The study has been important in investigating long-term predictors of cardiovascular morbidity and mortality, as well as investigating a broad spectrum of epidemiological and public health perspectives.<h4>Participants</h4>In 1972-1975, 2014 healthy men, 40-59 years old, were enrolled in the study. Comprehensive clinical examination included an ECG-monitored exercise test at baseline and follow-ups. The cohort has been re-examined four times during 20 years. Linkage to health records and national health registries has ensured complete endpoint2021-01-01T00:00:00Z2021 Oct2025-04-04T13:57:47.507Z2025-04-04T13:57:47.507ZS-EPMC85154263464566210.1136/bmjopen-2021-049111