{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["28(12)"],"submitter":["von Konow A"],"funding":["Lund University"],"pubmed_abstract":["<h4>Background</h4>Approximately 80% of soft tissue sarcoma (STS) recurrences, local and metastatic disease, are diagnosed within the first 3 years after primary diagnosis and treatment. Recurrences, however, can present after a longer period of remission. Our goal was to identify factors that may predict the risk of late recurrence.<h4>Methods</h4>We identified 677 patients with STS of the extremities and trunk wall from a population-based sarcoma register. Of these, 377 patients were alive and event-free at 3 years and were included for analysis of possible risk factors for late recurrence.<h4>Results</h4>Fifty-five of 377 (15%) patients developed late recurrence: 23 local recurrence, 21 metastasis, and 11 both manifestations. With R0 wide surgical margin as reference, R0 marginal (hazar"],"journal":["Annals of surgical oncology"],"pagination":["7891-7902"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8519908"],"repository":["biostudies-literature"],"pubmed_title":["Late Local Recurrence and Metastasis in Soft Tissue Sarcoma of the Extremities and Trunk Wall: Better Outcome After Treatment of Late Events Compared with Early."],"pmcid":["PMC8519908"],"pubmed_authors":["Styring E","Vult von Steyern F","Ghanei I","von Konow A"],"additional_accession":[]},"is_claimable":false,"name":"Late Local Recurrence and Metastasis in Soft Tissue Sarcoma of the Extremities and Trunk Wall: Better Outcome After Treatment of Late Events Compared with Early.","description":"<h4>Background</h4>Approximately 80% of soft tissue sarcoma (STS) recurrences, local and metastatic disease, are diagnosed within the first 3 years after primary diagnosis and treatment. Recurrences, however, can present after a longer period of remission. Our goal was to identify factors that may predict the risk of late recurrence.<h4>Methods</h4>We identified 677 patients with STS of the extremities and trunk wall from a population-based sarcoma register. Of these, 377 patients were alive and event-free at 3 years and were included for analysis of possible risk factors for late recurrence.<h4>Results</h4>Fifty-five of 377 (15%) patients developed late recurrence: 23 local recurrence, 21 metastasis, and 11 both manifestations. With R0 wide surgical margin as reference, R0 marginal (hazar","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Nov","modification":"2025-04-19T06:07:17.938Z","creation":"2025-04-19T06:07:17.938Z"},"accession":"S-EPMC8519908","cross_references":{"pubmed":["33861406"],"doi":["10.1245/s10434-021-09942-8"]}}