biostudies-literatureUnknown22(1)Shome S<h4>Background</h4>Bovine milk contains extracellular vesicles (EVs) that play a role in cellular communication, acting in either an autocrine, paracrine, or an exocrine manner. The unique properties of the EVs protect the cargo against degradation. We profiled the ncRNAs (non-coding RNA) present in the EVs from seven dairy products - raw whole milk, heat-treated skim milk, homogenized heat-treated skim milk, pasteurized homogenized skim milk, pasteurized heavy whipping cream, sweet cream buttermilk and cultured buttermilk with four replicates each, obtained at different processing steps from a commercial dairy plant. EVs and their cargo were extracted by using a validated commercial kit that has been shown to be efficient and specific for EVs. Further, to find the annotation of ncRNAs, weBMC genomics749https://www.ebi.ac.uk/biostudies/studies/S-EPMC8520644biostudies-literatureNon-coding RNA in raw and commercially processed milk and putative targets related to growth and immune-response.PMC8520644Jernigan RLShome SBeitz DCClark STestroet EDfalseNon-coding RNA in raw and commercially processed milk and putative targets related to growth and immune-response.<h4>Background</h4>Bovine milk contains extracellular vesicles (EVs) that play a role in cellular communication, acting in either an autocrine, paracrine, or an exocrine manner. The unique properties of the EVs protect the cargo against degradation. We profiled the ncRNAs (non-coding RNA) present in the EVs from seven dairy products - raw whole milk, heat-treated skim milk, homogenized heat-treated skim milk, pasteurized homogenized skim milk, pasteurized heavy whipping cream, sweet cream buttermilk and cultured buttermilk with four replicates each, obtained at different processing steps from a commercial dairy plant. EVs and their cargo were extracted by using a validated commercial kit that has been shown to be efficient and specific for EVs. Further, to find the annotation of ncRNAs, we2021-01-01T00:00:00Z2021 Oct2026-05-02T03:15:57.683Z2024-11-09T14:14:54.162ZS-EPMC85206443465759510.1186/s12864-021-07964-w