biostudies-literatureSong SScientific Research Grants of Chongqing Health Center for Women and ChildrenJoint Scientific Research Grants of Chongqing Health Commission and Science and Technology Bureau701https://www.ebi.ac.uk/biostudies/studies/S-EPMC8522257biostudies-literatureUnknown21(1)<h4>Background</h4>Mirror syndrome (MS) is defined as maternal edema with fetal hydrops and placental edema with different etiologies, such as rhesus isoimmunization and twin-twin transfusion syndrome. Herein, we showcased a unique MS case secondary to fetomaternal hemorrhage (FMH).<h4>Case presentation</h4>A 32-year-old gravida 2 para 0 woman diagnosed with fetal hydrops was admitted to our hospital. Maternal laboratory tests revealed anemia, slightly increased creatinine and uric acid levels, hypoproteinemia, and significantly increased alpha-fetoprotein and hemoglobin-F levels. Therefore, FMH was diagnosed initially. Two days after admission, the woman had unexpectedly progressive anasarca and started to feel chest distress, palpitations, lethargy, and oliguria, and MS was suspected. AnBMC pregnancy and childbirthA very preterm infant born to mother of mirror syndrome secondary to fetomaternal hemorrhage: a case report.PMC85222572019YJQN012021MSXM116Zhou LZhu YJorch GZhang XChen WSong SZhong XWang XWu YGong HfalseA very preterm infant born to mother of mirror syndrome secondary to fetomaternal hemorrhage: a case report.<h4>Background</h4>Mirror syndrome (MS) is defined as maternal edema with fetal hydrops and placental edema with different etiologies, such as rhesus isoimmunization and twin-twin transfusion syndrome. Herein, we showcased a unique MS case secondary to fetomaternal hemorrhage (FMH).<h4>Case presentation</h4>A 32-year-old gravida 2 para 0 woman diagnosed with fetal hydrops was admitted to our hospital. Maternal laboratory tests revealed anemia, slightly increased creatinine and uric acid levels, hypoproteinemia, and significantly increased alpha-fetoprotein and hemoglobin-F levels. Therefore, FMH was diagnosed initially. Two days after admission, the woman had unexpectedly progressive anasarca and started to feel chest distress, palpitations, lethargy, and oliguria, and MS was suspected. An2021-01-01T00:00:00Z2021 Oct2025-04-04T09:26:55.634Z2025-04-04T09:26:55.634ZS-EPMC85222573466323910.1186/s12884-021-04179-5