{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Beghi E"],"funding":["World Health Organization"],"pagination":["2265-2274"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8528941"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["269(5)"],"pubmed_abstract":["Acute and post-acute neurological symptoms, signs and diagnoses have been documented in an increasing number of patients infected by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which causes Coronavirus Disease 2019 (COVID-19). In this review, we aimed to summarize the current literature addressing neurological events following SARS-CoV-2 infection, discuss limitations in the existing literature and suggest future directions that would strengthen our understanding of the neurological sequelae of COVID-19. The presence of neurological manifestations (symptoms, signs or diagnoses) both at the onset or during SARS-CoV-2 infection is associated with a more severe disease, as demonstrated by a longer hospital stay, higher in-hospital death rate or the continued presence of "],"journal":["Journal of neurology"],"pubmed_title":["Acute and post-acute neurological manifestations of COVID-19: present findings, critical appraisal, and future directions."],"pmcid":["PMC8528941"],"funding_grant_id":["001"],"pubmed_authors":["Frontera J","Westenberg E","Kivipelto M","Prasad K","Garcia-Azorin D","Mangialasche F","Mukaetova-Ladinska EB","Allegri R","Chowdhary N","Winkler AS","Beghi E","Guekht A","Giussani G"],"additional_accession":[]},"is_claimable":false,"name":"Acute and post-acute neurological manifestations of COVID-19: present findings, critical appraisal, and future directions.","description":"Acute and post-acute neurological symptoms, signs and diagnoses have been documented in an increasing number of patients infected by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which causes Coronavirus Disease 2019 (COVID-19). In this review, we aimed to summarize the current literature addressing neurological events following SARS-CoV-2 infection, discuss limitations in the existing literature and suggest future directions that would strengthen our understanding of the neurological sequelae of COVID-19. The presence of neurological manifestations (symptoms, signs or diagnoses) both at the onset or during SARS-CoV-2 infection is associated with a more severe disease, as demonstrated by a longer hospital stay, higher in-hospital death rate or the continued presence of ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 May","modification":"2025-05-18T12:29:45.207Z","creation":"2025-05-18T12:29:45.207Z"},"accession":"S-EPMC8528941","cross_references":{"pubmed":["34674005"],"doi":["10.1007/s00415-021-10848-4"]}}